Quattrin Teresa, Cao Ying, Paluch Rocco A, Roemmich James N, Ecker Michelle A, Epstein Leonard H
Department of Pediatrics, Women and Children's Hospital of Buffalo, Buffalo, New York;
Department of Epidemiology and Environmental Health, University at Buffalo, Buffalo, New York; and.
Pediatrics. 2017 Sep;140(3). doi: 10.1542/peds.2016-2755.
We translated family-based behavioral treatment (FBT) to treat children with overweight and obesity and their parents in the patient-centered medical home. We reported greater reductions in child and parent weight at 6 and 24 months compared with an attention-controlled information control (IC) group. This article reports the cost-effectiveness of long-term weight change for FBT compared with IC.
Ninety-six children 2 to 5 years of age with overweight or obesity and with parents who had a BMI ≥25 were randomly assigned to FBT or IC, and both received diet and activity education (12-month treatment and 12-month follow-up). Weight loss and cost-effectiveness were assessed at 24 months. Intention-to-treat, completers, and sensitivity analyses were performed.
The average societal cost per family was $1629 for the FBT and $886 for the IC groups at 24 months. At 24 months, child percent over BMI (%OBMI) change decreased by 2.0 U in the FBT group versus an increase of 4.4 U in the IC group. Parents lost 6.0 vs 0.2 kg at 24 months in the FBT and IC groups, respectively. The incremental cost-effectiveness ratios (ICERs) for children and parents' %OBMI were $116.1 and $83.5 per U of %OBMI, respectively. Parental ICERs were also calculated for body weight and BMI and were $128.1 per 1, and $353.8/ per kilogram, respectively. ICER values for child %OBMI were similar in the intention-to-treat group ($116.1/1 U decrease) compared with completers ($114.3).
For families consisting of children and parents with overweight, FBT presents a more cost-effective alternative than an IC group.
我们在以患者为中心的医疗之家对基于家庭的行为治疗(FBT)进行了调整,用于治疗超重和肥胖儿童及其父母。我们报告称,与注意力控制信息对照组(IC组)相比,在6个月和24个月时,儿童和父母的体重下降幅度更大。本文报告了FBT与IC相比长期体重变化的成本效益。
96名2至5岁超重或肥胖儿童及其BMI≥25的父母被随机分配到FBT组或IC组,两组均接受饮食和活动教育(12个月治疗和12个月随访)。在24个月时评估体重减轻情况和成本效益。进行了意向性分析、完成者分析和敏感性分析。
24个月时,FBT组每个家庭的平均社会成本为1629美元,IC组为886美元。在24个月时,FBT组儿童BMI超标百分比(%OBMI)变化下降了2.0个单位,而IC组增加了4.4个单位。FBT组和IC组的父母在24个月时分别减重6.0千克和0.2千克。儿童和父母%OBMI的增量成本效益比(ICER)分别为每%OBMI单位116.1美元和83.5美元。还计算了父母体重和BMI的ICER,分别为每千克128.1美元和每千克353.8美元。意向性分析组中儿童%OBMI的ICER值(每降低1个单位116.1美元)与完成者组(114.3美元)相似。
对于由超重儿童及其父母组成的家庭,FBT比IC组是一种更具成本效益的选择。