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FRESH-teen 研究设计:一项评价针对超重或肥胖青少年及其家长的适应性情绪调节减肥方案的随机对照试验

Design of the FRESH-teen study: A randomized controlled trial evaluating an adapted emotion regulation weight loss program for adolescents with overweight or obesity and their parent.

机构信息

Department of Pediatrics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA; Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA.

Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA; San Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, USA.

出版信息

Contemp Clin Trials. 2024 Oct;145:107640. doi: 10.1016/j.cct.2024.107640. Epub 2024 Jul 28.

DOI:10.1016/j.cct.2024.107640
PMID:39079614
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11412776/
Abstract

Overweight and obesity affect >40% of adolescents. Family-based behavioral treatment (FBT) is the most efficacious behavioral treatment for weight management among youth and consists of nutrition and physical activity education, behavior change skills, and parent skills training. However, the efficacy of FBT decreases for youth as they get older. Increased emotional lability and limited emotion regulation skills may contribute to the reduced efficacy of FBT for adolescents. To date, there are no treatments for overweight or obesity specifically adapted for the needs of adolescents. We developed a treatment that integrates components from Dialectical Behavior Therapy and Emotion Focused Therapy with FBT (FBT+ER or FBT-ER) to address the specific needs of adolescents. The current study randomized 166 adolescents (BMI = 32.8; 14.3 years; 57% female; 32% Hispanic, 50% Non-Hispanic White, 18% Non-Hispanic and Non-White) and one of their parents (BMI = 32.9; 45.3 years; 85% female; 27% Hispanic, 57% Non-Hispanic White, 16% Non-Hispanic and Non-White) to 6 months of either standard FBT or FBT+ at 2 sites. Assessments were conducted at baseline, mid-treatment (month 3), post-treatment (month 6), 6-month follow-up (month 12) and 12-month follow-up (month 18). Primary outcomes are adolescent weight (BMIz/%BMIp95), emotion regulation skills, and emotional eating behaviors. Given the public health concern of adolescent obesity, FBT+ could prove extremely useful to provide more targeted and effective intervention for adolescents with overweight or obesity. CLINICAL TRIALS: # NCT03674944.

摘要

超重和肥胖影响超过 40%的青少年。基于家庭的行为治疗 (FBT) 是青少年体重管理最有效的行为治疗方法,包括营养和身体活动教育、行为改变技能和家长技能培训。然而,随着青少年年龄的增长,FBT 的疗效会降低。情绪不稳定和有限的情绪调节技能的增加可能导致 FBT 对青少年的疗效降低。迄今为止,还没有专门针对青少年需求的超重或肥胖治疗方法。我们开发了一种治疗方法,将辩证行为疗法和情绪焦点疗法的成分与 FBT 相结合 (FBT+ER 或 FBT-ER),以满足青少年的特殊需求。目前的研究将 166 名青少年 (BMI=32.8; 14.3 岁; 57%为女性; 32%为西班牙裔,50%为非西班牙裔白人,18%为非西班牙裔和非白种人) 和他们的一位家长 (BMI=32.9; 45.3 岁; 85%为女性; 27%为西班牙裔,57%为非西班牙裔白人,16%为非西班牙裔和非白种人) 随机分为两组,分别接受 6 个月的标准 FBT 或 FBT+治疗。评估在基线、治疗中期 (第 3 个月)、治疗后 (第 6 个月)、6 个月随访 (第 12 个月) 和 12 个月随访 (第 18 个月)进行。主要结局是青少年体重 (BMIz/%BMIp95)、情绪调节技能和情绪性进食行为。鉴于青少年肥胖的公共卫生问题,FBT+可能对为超重或肥胖的青少年提供更有针对性和更有效的干预措施非常有用。临床试验:# NCT03674944。

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