Muddathir A K, Balansard G, Timon-David P, Babadjamian A, Yogoub A K, Julien M J
J Pharm Pharmacol. 1987 Apr;39(4):296-300. doi: 10.1111/j.2042-7158.1987.tb06269.x.
A pure anthelmintic substance (PGA) has been isolated from the methanol-aqueous extract of the leaf of Polygonum glabrum Willd., a semi-aquatic Sudanese species of the family Polygonaceae. The antiparasitic in-vitro activity of several fractions isolated from the plant, has been examined comparatively with that of PGA. PGA also showed molluscicidal activity against Biomphalaria glabrata and Limnea truncatula Müll. Structural determination of PGA was attempted following data analysis of UV, IR, 13C NMR, 1H NMR and MS spectra and suggests that PGA is a terpenoid.
从蓼科一种半水生的苏丹植物——光蓼(Polygonum glabrum Willd.)叶片的甲醇水提取物中分离出了一种纯抗蠕虫物质(PGA)。已将从该植物中分离出的几个组分的体外抗寄生虫活性与PGA的活性进行了比较。PGA对光滑双脐螺(Biomphalaria glabrata)和截口土蜗(Limnea truncatula Müll.)也显示出杀螺活性。在对紫外光谱、红外光谱、13C核磁共振谱、1H核磁共振谱和质谱进行数据分析后,尝试对PGA进行结构测定,结果表明PGA是一种萜类化合物。