National Institutes for Food and Drug Control, China.
National Institutes for Food and Drug Control, China.
J Pharm Biomed Anal. 2018 Jan 5;147:81-88. doi: 10.1016/j.jpba.2017.08.016. Epub 2017 Aug 15.
Spurious/Falsely-labeled/Falsified/Counterfeit (SFFC)drugs have become a major threat to public health, especially in rural areas of developing countries.The goal of this review is to provide an overview of rapid detection technologies for counterfeits recently reported, such as Near Infrared Spectroscopy, Near Infrared Chemical Imaging, Raman Spectroscopy, X-Ray Fluorescence, X-RayPowder Diffraction, Ion Mobility Spectrometry, Ion MobilityMass Spectrometry,Isotope Ratio Mass Spectrometry and visual analytical methods The advantages of each of these detection methods are introduced. Examples of characterization of SFFC drugs using the detection technology mentioned are presented. In addition, new characteristics and trends of SFFC drugs are listed and the solution is discussed.
假冒伪劣/虚假标签/伪造/伪造（SFFC）药品已成为公共卫生的主要威胁，尤其是在发展中国家的农村地区。本综述的目的是提供最近报道的假冒伪劣快速检测技术的概述，如近红外光谱、近红外化学成像、拉曼光谱、X 射线荧光、X 射线粉末衍射、离子迁移光谱、离子迁移质谱、同位素比质谱和可视化分析方法。介绍了每种检测方法的优点。介绍了使用所述检测技术对 SFFC 药物进行特征描述的示例。此外，列出了 SFFC 药物的新特征和趋势，并讨论了解决方案。
