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一名免疫抑制的淋巴瘤患者手部发生播散性隐球菌骨髓炎。

Disseminated Cryptococcal Osteomyelitis to the Hand in an Immunosuppressed Lymphoma Patient.

作者信息

Chen Wayne A, Emory Cynthia L, Graves Benjamin R

机构信息

Department of Orthopaedic Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC.

Department of Orthopaedic Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC.

出版信息

J Hand Surg Am. 2018 Mar;43(3):291.e1-291.e6. doi: 10.1016/j.jhsa.2017.07.013. Epub 2017 Aug 26.

Abstract

Fungal osteomyelitis of the hand is rare with limited evidence-based literature to guide diagnosis and management. We report a case of disseminated cryptococcal osteomyelitis in the middle phalanx from a pulmonary fungal infection in a patient with a history of lymphoplasmacytic lymphoma. Although rare, cryptococcosis should be considered in the differential diagnosis of aggressive lytic lesions with bone pain and associated large soft tissue masses, especially in the immunosuppressed host.

摘要

手部真菌性骨髓炎较为罕见,缺乏基于证据的文献来指导诊断和治疗。我们报告一例有淋巴浆细胞淋巴瘤病史的患者因肺部真菌感染导致中节指骨播散性隐球菌骨髓炎的病例。尽管罕见,但在鉴别诊断伴有骨痛和相关大软组织肿块的侵袭性溶骨性病变时,尤其是在免疫抑制宿主中,应考虑隐球菌病。

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