Mokhtar N Hafizah, Abas Aizat, Razak N A, Hamid Muhammad Najib Abdul, Teong Soon Lay
School of Mechanical Engineering, Universiti Sains Malaysia, Engineering Campus, Nibong Tebal, Penang 14300, Malaysia.
School of Mechanical Engineering, Universiti Sains Malaysia, Engineering Campus, Nibong Tebal, Penang 14300, Malaysia.
J Theor Biol. 2017 Nov 21;433:73-84. doi: 10.1016/j.jtbi.2017.08.016. Epub 2017 Aug 24.
Proper design of stent for application at specific aneurysm effect arteries could help to reduce the issues with thrombosis and aneurysm. In this paper, four types of stent configuration namely half-Y (6 mm), half-Y (4 mm), cross-bar, and full-Y configuration will implanted on real 3D artery bifurcation aneurysm effected arteries. Comparisons were then conducted based on the flow patterns after stent placement using both LBM-based solver and PIV experimental findings. According to the data obtained from all 4 stent designs, the flow profiles and the computed velocity from both methods were in agreement with each other. Both methods found that half-Y (6 mm) stent configuration is by far the best configuration in reducing the blood velocity at the vicinity of the aneurysm sac. The analysis also show that the half-Y (6 mm) stent configuration recorded the highest percentage of velocity reduction and managed to substantially reduce the pressure at the bifurcation region. This high flow velocity reduction through the use of half-Y stent could consequently promote the formation of thrombus thereby reducing the risk of rupture in the aneurysm sac.
针对特定动脉瘤影响动脉设计合适的支架有助于减少血栓形成和动脉瘤相关问题。本文中，将四种类型的支架结构，即半Y型（6毫米）、半Y型（4毫米）、横杆型和全Y型结构，植入真实的三维动脉分叉动脉瘤影响的动脉上。然后使用基于格子玻尔兹曼方法（LBM）的求解器和粒子图像测速（PIV）实验结果，根据支架植入后的血流模式进行比较。根据从所有4种支架设计获得的数据，两种方法得到的流动剖面和计算速度彼此一致。两种方法均发现，半Y型（6毫米）支架结构是目前在降低动脉瘤囊附近血流速度方面的最佳结构。分析还表明，半Y型（6毫米）支架结构记录的速度降低百分比最高，并成功大幅降低了分叉区域的压力。通过使用半Y型支架实现的这种高血流速度降低可能会促进血栓形成，从而降低动脉瘤囊破裂的风险。
