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基于格子玻尔兹曼方法的冠状动脉血流储备分数无创数值模拟

[Noninvasive numerical simulation of coronary fractional flow reserve based on lattice Boltzmann method].

作者信息

Liu Rongting, Yang Qingqing, Qiao Aike, Hou Yang, Ma Yue

机构信息

College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, P.R.China.

College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124,

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 Jun 25;35(3):384-389. doi: 10.7507/1001-5515.201710034.

DOI:10.7507/1001-5515.201710034
PMID:29938945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9935220/
Abstract

In order to investigate the application of lattice Boltzmann method (LBM) in the numerical simulation of computed tomography angiography-derived fractional flow reserve (FFR ), an idealized narrowed tube model and two coronary stenosis arterymodels are studied. Based on the open source code library (Palabos), the relative algorithm program in the development environment (Codeblocks) was improved. Through comparing and analyzing the results of FFR which is simulated by LBM and finite element analysis software ANSYS, and the feasibility of the numerical simulation of FFR by LBM was verified . The results show that the relative error between the results of LBM and finite element analysis software ANSYS is about 1%, which vertifies the feasibility of simulating the coronary FFR by LBM. The simulation of this study provides technical support for developing future FFR application software, and lays the foundation for the calculation of clinical FFR .

摘要

为了研究格子玻尔兹曼方法(LBM)在计算机断层扫描血管造影衍生的血流储备分数(FFR)数值模拟中的应用,研究了一个理想化的狭窄管模型和两个冠状动脉狭窄动脉模型。基于开源代码库(Palabos),对开发环境(Codeblocks)中的相关算法程序进行了改进。通过比较和分析LBM模拟的FFR结果与有限元分析软件ANSYS模拟的结果,验证了LBM对FFR进行数值模拟的可行性。结果表明,LBM结果与有限元分析软件ANSYS结果之间的相对误差约为1%,验证了用LBM模拟冠状动脉FFR的可行性。本研究的模拟为未来FFR应用软件的开发提供了技术支持,并为临床FFR的计算奠定了基础。

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