Biberoğlu Esra, Eraslan Muhsin, Baltacıoğlu Feyyaz, Midi İpek
Marmara University Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey.
Marmara University Faculty of Medicine, Department of Diagnostic and Interventional Radiology, İstanbul, Turkey.
Turk J Ophthalmol. 2017 Aug;47(4):192-197. doi: 10.4274/tjo.67809. Epub 2017 Aug 15.
The aim of this study was to evaluate intraocular pressure (IOP) and retinal nerve fiber layer (RNFL) changes in patients with carotid artery stenosis (CAS) after carotid artery stenting.
This study was conducted as a cross-sectional, non-randomised clinical case series. Fifteen male patients (mean age: 63.6±9.1) with CAS and more than 70% carotid artery narrowing were included. All of the patients were followed in the department of neurology and were operated in the interventional radiology division. Eighteen healthy male subjects (mean age: 63.7±5.3) were included in the control group. All of the healthy subjects had a detailed ophthalmological examination and subjects with any chronic eye disease were excluded from the study. All of the participants had a detailed ophthalmological examination including tonometry using Goldmann applanation tonometry and RNFL analysis using optical coherence tomography (RTVue-100 5.1).
There were no ocular ischemic symptoms in any of the participants. The mean IOP value was 15.1±2.1 mmHg in the control group and 16.6±2.4 mmHg before stent implantation, 16.4±2.2 mmHg at 1 week after implantation, 16.6±2.5 mmHg at 1 month after implantation, and 16.7±2.9 mmHg at 3 months after implantation in the CAS group. Mean RNFL thickness was 105±6 µm in the control group; in the CAS group, mean RNFL thickness values were 98±27 µm before stent implantation and 103±11 µm, 101±10 µm, and 101±11 µm at 1 week, 1 month, and 3 months after stenting. There were no significant differences between the CAS group and control group regarding IOP and RNFL thickness values (p>0.05). IOP and RNFL thickness also did not show any statistically significant changes from preoperative measurements in 3 months postoperative follow-up in the CAS group (p>0.05).
IOP and RNFL thickness remained unchanged after carotid stent implantation in carotid artery stenosis patients with no signs of ocular ischemic syndrome.
本研究旨在评估颈动脉支架置入术后颈动脉狭窄（CAS）患者的眼压（IOP）和视网膜神经纤维层（RNFL）变化。
本研究作为一项横断面、非随机的临床病例系列进行。纳入15例男性患者（平均年龄：63.6±9.1岁），其患有CAS且颈动脉狭窄超过70%。所有患者均在神经科接受随访，并在介入放射科接受手术。对照组纳入18例健康男性受试者（平均年龄：63.7±5.3岁）。所有健康受试者均接受了详细的眼科检查，患有任何慢性眼病的受试者被排除在研究之外。所有参与者均接受了详细的眼科检查，包括使用Goldmann压平眼压计测量眼压以及使用光学相干断层扫描（RTVue - 100 5.1）进行RNFL分析。
所有参与者均无眼部缺血症状。对照组的平均眼压值为15.1±2.1 mmHg，CAS组在支架植入前为16.6±2.4 mmHg，植入后1周为16.4±2.2 mmHg，植入后1个月为16.6±2.5 mmHg，植入后3个月为16.7±2.9 mmHg。对照组的平均RNFL厚度为105±6 µm；在CAS组中，支架植入前的平均RNFL厚度值为98±27 µm，支架置入后1周、1个月和3个月分别为103±11 µm、101±10 µm和101±11 µm。CAS组和对照组在眼压和RNFL厚度值方面无显著差异（p>0.05）。在CAS组术后3个月的随访中，眼压和RNFL厚度与术前测量值相比也未显示出任何统计学上的显著变化（p>0.05）。
在没有眼部缺血综合征迹象的颈动脉狭窄患者中，颈动脉支架植入术后眼压和RNFL厚度保持不变。
