Atwell R B, Seiler R
Aust Vet J. 1978 Dec;54(12):585-7. doi: 10.1111/j.1751-0813.1978.tb02417.x.
Primary osteosarcoma of the fifth sternebra is reported in a 6-year-old male Great Dane. Presenting signs were suggestive of myocarditis and pulmonary congestion. Electrocardiography revealed R waves of low and variable amplitude and the plasma alpha-hydroxibutyrate dehydrogenase level was elevated. Radiography revealed neoplasia of the fifth sternebra with extensive bilaterial pulmonary metastases. Histologically the neoplasm showed typical osteosarcoma with plentiful osteoid production.
一只6岁的雄性大丹犬被报道患有第五胸骨原发性骨肉瘤。临床表现提示心肌炎和肺充血。心电图显示R波低平且幅度可变，血浆α-羟丁酸脱氢酶水平升高。放射学检查显示第五胸骨有肿瘤形成并伴有广泛的双侧肺转移。组织学上，肿瘤表现为典型的骨肉瘤，有大量类骨质生成。
