Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences (USUHS), 4301 Jones Bridge Road, Bethesda, MD 20814, USA.
Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), US Department of Health and Human Services (DHHS), 10 Center Drive, Bethesda, MD 20892, USA.
Nutrients. 2017 Aug 28;9(9):947. doi: 10.3390/nu9090947.
Interpersonal psychotherapy (IPT) prevents weight gain and reduces loss-of-control (LOC)-eating in adults. However, IPT was not superior to health-education (HE) for preventing excess weight gain and reducing LOC-eating over 1-year in adolescent girls at risk for excess weight gain and eating disorders. Limited data suggest that older and non-White youth may be especially responsive to IPT. In secondary analyses, we examined if age or race moderated weight and LOC-eating outcomes. The 113 participants (12-17 years; 56.6% White) from the original trial were re-contacted 3 years later for assessment. At baseline and follow-up visits through 3 years, we assessed BMI, adiposity by dual energy X-ray absorptiometry, and LOC-eating presence. In linear mixed models, baseline age moderated 3-year BMI outcome; older girls in IPT had the lowest 3-year BMI gain compared to younger girls in IPT and all girls in HE, = 0.04. A similar pattern was observed for adiposity. Race moderated 3-year LOC-eating; non-White girls in IPT were most likely to abstain from LOC-eating at 3 years compared to all other girls, = 0.04. This hypothesis-generating analysis suggests future studies should determine if IPT is especially efficacious at reducing LOC-eating in older, non-White adolescents.
人际心理治疗 (IPT) 可预防体重增加和减少成年人的失控性进食 (LOC)。然而，IPT 在预防超重和减少 1 年内超重和饮食失调风险的青少年女性的 LOC 进食方面并不优于健康教育 (HE)。有限的数据表明，年龄较大和非白人的年轻人可能对 IPT 更敏感。在二次分析中，我们检查了年龄或种族是否调节体重和 LOC 进食结果。来自原始试验的 113 名参与者（12-17 岁；56.6% 为白人）在 3 年后再次接受评估。在基线和随访期间，我们通过 3 年评估 BMI、双能 X 射线吸收法测量的肥胖程度和 LOC 进食的存在情况。在线性混合模型中，基线年龄调节了 3 年 BMI 结果；IPT 中的年龄较大的女孩与 IPT 中的年龄较小的女孩和 HE 中的所有女孩相比，3 年内 BMI 增长最低， = 0.04。肥胖程度也观察到了类似的模式。种族调节了 3 年 LOC 进食；IPT 中的非白人女孩与其他所有女孩相比，最有可能在 3 年内避免 LOC 进食， = 0.04。这项产生假设的分析表明，未来的研究应该确定 IPT 是否特别有效地减少年龄较大、非白人青少年的 LOC 进食。
