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递增预测效度的成瘾严重程度指数精神病复合分数在连续队列的病人住院治疗的药物使用障碍。

Incremental predictive validity of the Addiction Severity Index psychiatric composite score in a consecutive cohort of patients in residential treatment for drug use disorders.

机构信息

Aarhus University, Centre for Alcohol and Drug Research, Bartholins Allé 10, 8000 Aarhus C, Denmark.

出版信息

Addict Behav. 2018 Jan;76:201-207. doi: 10.1016/j.addbeh.2017.08.006. Epub 2017 Aug 22.

Abstract

BACKGROUND

The Addiction Severity Index (ASI) is a widely used assessment instrument for substance abuse treatment that includes scales reflecting current status in seven potential problem areas, including psychiatric severity. The aim of this study was to assess the ability of the psychiatric composite score to predict suicide and psychiatric care after residential treatment for drug use disorders after adjusting for history of psychiatric care.

METHODS

All patients treated for drug use disorders in residential treatment centers in Denmark during the years 2000-2010 with complete ASI data were followed through national registers of psychiatric care and causes of death (N=5825). Competing risks regression analyses were used to assess the incremental predictive validity of the psychiatric composite score, controlling for previous psychiatric care, length of intake, and other ASI composite scores, up to 12years after discharge.

RESULTS

A total of 1769 patients received psychiatric care after being discharged from residential treatment (30.3%), and 27 (0.5%) committed suicide. After adjusting for all covariates, psychiatric composite score was associated with a higher risk of receiving psychiatric care after residential treatment (subhazard ratio [SHR]=3.44, p<0.001), and of committing suicide (SHR=11.45, p<0.001).

CONCLUSIONS

The ASI psychiatric composite score has significant predictive validity and promises to be useful in identifying patients with drug use disorders who could benefit from additional mental health treatment.

摘要

背景

成瘾严重程度指数(ASI)是一种广泛用于物质滥用治疗的评估工具,包括反映七个潜在问题领域当前状况的量表,包括精神疾病严重程度。本研究的目的是评估精神病学综合评分在调整精神卫生保健史后,对药物使用障碍住院治疗后自杀和精神卫生保健的预测能力。

方法

在 2000 年至 2010 年间,丹麦所有在住院治疗中心接受药物使用障碍治疗且 ASI 数据完整的患者均通过国家精神卫生保健和死因登记处进行随访(N=5825)。采用竞争风险回归分析评估精神病学综合评分的增量预测效度,在调整了先前的精神卫生保健、摄入时长和其他 ASI 综合评分后,在出院后 12 年内进行评估。

结果

共有 1769 名患者在出院后接受了精神卫生保健(30.3%),27 人(0.5%)自杀。在调整了所有协变量后,精神病学综合评分与住院治疗后接受精神卫生保健的风险增加相关(亚危险比[SHR]=3.44,p<0.001),与自杀风险增加相关(SHR=11.45,p<0.001)。

结论

ASI 精神病学综合评分具有显著的预测效度,有望用于识别可能受益于额外心理健康治疗的药物使用障碍患者。

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