Sanchez Conde Matilde, Vivancos Gallego María Jesús, Moreno Guillen Santiago
Infectious Disease Unit, Hospital Ramón y Cajal, Madrid. Instituto Ramón y Cajal de Investigación Sanitaria (Ramón y Cajal Health Research Institute) (IRYCIS), Madrid..
Infectious Disease Unit, Hospital Ramón y Cajal, Madrid. Instituto Ramón y Cajal de Investigación Sanitaria (Ramón y Cajal Health Research Institute) (IRYCIS), Madrid. Department of Medicine, University of Alcalá de Henares, Madrid..
Farm Hosp. 2017 Sep 1;41(5):630-637. doi: 10.7399/fh.10821.
Despite the global stabilization of the number of new HIV infections in recent years, there has been an increase in new infections among men who have sex with men. This fact indicates the lack of effectiveness of the measures and prevention campaigns established so far for this group. It is therefore necessary to implement alternative preventive measures for them. Pre-exposure pharmacological prophylaxis (PrEP) is one of the best evaluated options and has had high protection rates in both clinical and real-life trials. The strategy has also shown an adequate profile in terms of safety, tolerance, adverse effects and cost-effectiveness in the studies carried out to assess this important topic.
尽管近年来全球新增艾滋病毒感染人数趋于稳定，但男男性行为者中的新感染病例却有所增加。这一事实表明，迄今为止为该群体制定的措施和预防活动缺乏成效。因此，有必要为他们实施替代性预防措施。暴露前药物预防（PrEP）是评估效果最佳的选择之一，在临床试验和实际生活试验中均具有很高的保护率。在评估这一重要课题的研究中，该策略在安全性、耐受性、不良反应和成本效益方面也显示出良好表现。
