Gill T J, Kunz H W, Misra D N, Hassett A L
Transplantation. 1987 Jun;43(6):773-85.
Immunogenetic studies in the rat began with the investigation of blood group antigens (1-7) and evolved into the investigation of histocompatibility antigens and transplantation phenomena (8-17). In the course of this work, several nomenclature systems evolved that were eventually reconciled in a series of comparison studies (18-24). The biennial Workshops on Alloantigenic Systems in the Rat held under the aegis of the Transplantation Society (24) have provided the forum for the continued evolution of this field. In addition, several reviews (24-31) and books (32-35) have provided periodic summaries of different aspects of rat immunogenetics. This review will focus on the structure of the major histocompatibility complex (MHC) of the rat from the serological, biochemical, and molecular points of view.
大鼠的免疫遗传学研究始于血型抗原的研究（1-7），并发展为组织相容性抗原和移植现象的研究（8-17）。在这项工作过程中，出现了几种命名系统，最终在一系列比较研究中得以统一（18-24）。在移植学会的主持下每两年举办一次的大鼠同种异体抗原系统研讨会（24）为该领域的持续发展提供了平台。此外，几篇综述（24-31）和书籍（32-35）对大鼠免疫遗传学的不同方面进行了定期总结。本综述将从血清学、生物化学和分子角度重点介绍大鼠主要组织相容性复合体（MHC）的结构。
