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创建用于预测儿童和青少年附件扭转的综合评分

Creation of a Composite Score to Predict Adnexal Torsion in Children and Adolescents.

作者信息

Schwartz Beth I, Huppert Jill S, Chen Chen, Huang Bin, Reed Jennifer L

机构信息

Division of Pediatric and Adolescent Gynecology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Division of Pediatric and Adolescent Gynecology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

出版信息

J Pediatr Adolesc Gynecol. 2018 Apr;31(2):132-137. doi: 10.1016/j.jpag.2017.08.007. Epub 2017 Aug 26.

Abstract

STUDY OBJECTIVE

To create a composite score to predict adnexal torsion in children and adolescents.

DESIGN

A prospective cross-sectional study.

SETTING

Emergency department of a tertiary care children's hospital.

PARTICIPANTS

Three hundred twenty-four female participants aged 6-21 years who presented to the emergency department with lower abdominal pain and underwent ultrasound or computed tomography imaging.

INTERVENTIONS

Collection of possible clinical and radiologic predictors of torsion.

MAIN OUTCOME MEASURES

The primary outcome was a composite score to predict adnexal torsion. We used χ analyses to identify possible risk factors. The classification and regression tree decision method was used to identify risk factor cutoff points. Independent risk factors were combined into a composite score. Receiver operating characteristic curve analyses were used to assessed score performance.

RESULTS

Of 324 participants with abdominal pain, 241 underwent imaging, and 6.6% (16 of 241) had torsion. Duration of pain, intermittent pain, nausea, and absence of arterial or venous flow were not associated with torsion. Vomiting (P = .05 in premenarchal subjects; P < .001 in menarchal subjects), adnexal volume (P = .008 in premenarchal subjects; P < .001 in menarchal subjects), and adnexal volume ratio (P = .04 in premenarchal subjects; P < .001 in menarchal subjects) were independent predictors of torsion. These predictors were incorporated into a composite score. No torsions were identified with a score of less than 2. There was an increasing risk of torsion for each 1-point score increase.

CONCLUSION

Independent predictors of torsion can reliably be combined into a composite score to identify children and adolescents at risk for adnexal torsion. This score might aid in improving triage and management of these challenging patients.

摘要

研究目的

创建一个综合评分来预测儿童和青少年附件扭转。

设计

一项前瞻性横断面研究。

地点

一家三级护理儿童医院的急诊科。

参与者

324名6至21岁的女性参与者,她们因下腹痛到急诊科就诊并接受了超声或计算机断层扫描成像。

干预措施

收集扭转可能的临床和放射学预测因素。

主要观察指标

主要结局是预测附件扭转的综合评分。我们使用χ分析来确定可能的危险因素。采用分类与回归树决策方法确定危险因素的截断点。将独立危险因素合并为一个综合评分。采用受试者工作特征曲线分析来评估评分性能。

结果

在324名腹痛参与者中,241人接受了成像检查,其中6.6%(241人中的16人)发生了扭转。疼痛持续时间、间歇性疼痛、恶心以及无动脉或静脉血流与扭转无关。呕吐(青春期前受试者P = 0.05;青春期后受试者P < 0.001)、附件体积(青春期前受试者P = 0.008;青春期后受试者P < 0.001)和附件体积比(青春期前受试者P = 0.04;青春期后受试者P < 0.001)是扭转的独立预测因素。这些预测因素被纳入一个综合评分。评分低于2分时未发现扭转病例。评分每增加1分,扭转风险增加。

结论

扭转的独立预测因素可以可靠地合并为一个综合评分,以识别有附件扭转风险的儿童和青少年。该评分可能有助于改善对这些具有挑战性患者的分诊和管理。

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