Georgesen Corey, Kheterpal Meenal, Pulitzer Melissa
Department of Dermatology, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Case Rep Pathol. 2017;2017:3032941. doi: 10.1155/2017/3032941. Epub 2017 Aug 7.
Cutaneous and systemic plasmacytosis are reactive disease processes that occur in middle-aged Japanese and Chinese men. Systemic plasmacytosis, defined by plasmacytic infiltration of two organ systems, might rarely progress to lymphoma. Cutaneous plasmacytosis, however, is chronic and benign and is characterized by the development of multiple plasma cell-rich infiltrates in the skin. We present a case of cutaneous plasmacytosis in a 46-year-old Korean male. The patient demonstrated classic features of the disease entity, including disseminated red-brown plaques, differentiated plasmacytoid infiltrates on biopsy, hypergammaglobulinemia, and the absence of systemic disease.
皮肤和系统性浆细胞增多症是发生在中年日本和中国男性中的反应性疾病过程。系统性浆细胞增多症由两个器官系统的浆细胞浸润所定义,可能很少进展为淋巴瘤。然而,皮肤浆细胞增多症是慢性且良性的,其特征是皮肤中出现多个富含浆细胞的浸润灶。我们报告一例46岁韩国男性的皮肤浆细胞增多症病例。该患者表现出该疾病实体的典型特征,包括散在的红棕色斑块、活检显示分化的浆细胞样浸润、高球蛋白血症以及无全身性疾病。