Shadel Brooke N, Frater John L, Gapp Joshua D G, Hurley M Yadira
Department of Dermatology, Saint Louis University School of Medicine, St Louis, MO 63104, USA.
J Cutan Pathol. 2010 Jun;37(6):697-702. doi: 10.1111/j.1600-0560.2009.01372.x. Epub 2009 Jul 15.
Cutaneous and systemic plasmacytosis is a rare condition primarily affecting middle-aged individuals of Japanese descent and has principally been reported in cases originating from Asia. Its relationship, if any, to Castleman disease, is controversial. The authors report a case of cutaneous and systemic plasmacytosis involving a 36-year-old man of Chinese ancestry born in North America. The biopsy of an involved lymph node revealed changes resembling Castleman disease. Significantly, this case to our knowledge represents the first case of cutaneous and systemic plasmacytosis presenting in a patient of Chinese ancestry born on the North American mainland.
皮肤及系统性浆细胞增多症是一种罕见疾病，主要影响日本裔中年个体，且主要在源自亚洲的病例中被报道。它与卡斯特曼病（Castleman disease）的关系（若存在关系的话）存在争议。作者报告了一例皮肤及系统性浆细胞增多症病例，患者为一名36岁出生于北美的华裔男子。对一个受累淋巴结的活检显示出类似于卡斯特曼病的变化。重要的是，据我们所知，该病例是北美大陆出生的华裔患者中首例出现的皮肤及系统性浆细胞增多症病例。
