Pushina Mariia, Anzenbacher Pavel
Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University, Bowling Green, OH 43403, USA.
Chem Commun (Camb). 2017 Sep 5;53(72):10074-10077. doi: 10.1039/c7cc05012g.
Biguanides are strong bases (pK > 10), their protonated forms bind anions and may therefore act as receptors for anions. We report on easy-to-make anion receptors and fluorescence-based sensors utilizing the biguanide moieties that respond to the presence of anions with a change in fluorescence. The observed changes in fluorescence are anion-specific and even though the biguanide receptors are cross-reactive, these sensors may be used to identify various anions (halides, carboxylates, phosphates). Paper-based analytical arrays were used to assess the discriminatory ability of the sensors in the qualitative and quantitative analysis of multiple anions.
双胍是强碱（pK>10），其质子化形式能结合阴离子，因此可作为阴离子受体。我们报道了利用双胍部分制成的易于制备的阴离子受体和基于荧光的传感器，这些传感器会因阴离子的存在而发生荧光变化。观察到的荧光变化具有阴离子特异性，尽管双胍受体具有交叉反应性，但这些传感器可用于识别各种阴离子（卤化物、羧酸盐、磷酸盐）。基于纸张的分析阵列用于评估传感器在多种阴离子定性和定量分析中的鉴别能力。
