Lvova Larisa, Caroleo Fabrizio, Garau Alessandra, Lippolis Vito, Giorgi Luca, Fusi Vieri, Zaccheroni Nelsi, Lombardo Marco, Prodi Luca, Di Natale Corrado, Paolesse Roberto
Department of Chemical Science and Technologies, University "Tor Vergata", Rome, Italy.
Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Monserrato, Italy.
Front Chem. 2018 Jun 28;6:258. doi: 10.3389/fchem.2018.00258. eCollection 2018.
The development of a novel all-solid-state optical sensor array based on heteroatomic macrocyclic fluorophores (diaza-crown ether, metallocorrole and pyridinophans) for the photographic analysis of liquid media, is presented. The sensitivity of the new optical system toward a number of different species (cations: Li, K, Na, , Mg, Ca, Co, Cu, Zn, Cd, Pb and anions: , , Cl, Br, ) was evaluated both in single selective sensor mode and in multisensory arrangement. The satisfactory PLS1 regression models between sensor array optical response and analyte concentration were obtained for Cd, Cu, Zn, and ions in all the range of tested concentrations. Among these species the highest attention was focused onto detection of cadmium and nitrite ions, for which the detection limits, DL, estimated by 3σ method were found 0.0013 mg/L and 0.21 mg/L respectively, and these values are lower than the corresponding WHO guideline values of 0.003 mg/L (Cd) and 2 mg/L ( ). The suitability of the developed sensors implemented with familiar devices for signal acquisition (Light Emitting Diode, LED, as light source and a digital camera as a signal detector), and chemometric methods for data treatment to perform fast and low-cost monitoring of species under interest, in real samples of environmental importance, is demonstrated.
本文介绍了一种基于杂原子大环荧光团（二氮杂冠醚、金属卟啉和吡啶环番）的新型全固态光学传感器阵列的开发，用于液体介质的照相分析。在单选择性传感器模式和多传感器配置下，评估了这种新型光学系统对多种不同物质（阳离子：Li、K、Na、 、Mg、Ca、Co、Cu、Zn、Cd、Pb；阴离子： 、 、Cl、Br、 ）的灵敏度。对于Cd、Cu、Zn和 离子，在所有测试浓度范围内，传感器阵列光学响应与分析物浓度之间均获得了令人满意的PLS1回归模型。在这些物质中，对镉和亚硝酸根离子的检测最为关注，通过3σ方法估计其检测限DL分别为0.0013 mg/L和0.21 mg/L，这些值低于世界卫生组织相应的指导值0.003 mg/L（Cd）和2 mg/L（ ）。本文展示了所开发的传感器与常见的信号采集设备（发光二极管LED作为光源，数码相机作为信号探测器）以及用于数据处理的化学计量学方法相结合，能够在具有环境重要性的实际样品中对感兴趣的物质进行快速、低成本监测的适用性。
