Almuklass Awad M, Feeney Daniel F, Mani Diba, Hamilton Landon D, Enoka Roger M
Department of Integrative Physiology, University of Colorado, Boulder, CO, 80309, USA.
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Exp Brain Res. 2017 Nov;235(11):3487-3493. doi: 10.1007/s00221-017-5075-4. Epub 2017 Aug 28.
Manual dexterity declines with advancing age and the development of neurological disorders. Changes in manual dexterity are frequently quantified as the time it takes to complete the grooved pegboard test, which requires individuals to manipulate 25 pegs. The manipulation of each peg involves four phases: selection, transport, insertion, and return. The purpose of the study was to compare the times to complete the four phases of manipulating each peg and the forces applied to the pegboard during peg selection and insertion in persons with multiple sclerosis (MS) and age- and sex-matched healthy adults. Multiple-regression models that could explain the variance in pegboard times for each group of participants were compared to assess the relative significance of the peg-manipulation attributes. The performance of 17 persons with MS (52.2 ± 8.3 years) was compared with 17 control subjects (52.2 ± 11.5 years). The grooved pegboard test was performed on a force plate. Pegboard times for the MS group (104 ± 40 s) were longer than those for the Control group (61 ± 15 s). Regression analysis indicated that the pegboard times for the MS group could be predicted by the time for the peg-selection phase (R = 0.78), whereas the predictors for Control group (R = 0.77) were the times for the peg-transport (partial r = 0.80) and selection (partial r = 0.58) phases. The variance in the time it took the MS participants to complete the grooved pegboard test was strongly related to the time required to select each peg, whereas the pegboard times for the Control subjects depended mostly on the duration of the transport phase but also on the time to select each peg.
随着年龄的增长和神经疾病的发展，手部灵活性会下降。手部灵活性的变化通常通过完成凹槽钉板测试所需的时间来量化，该测试要求个体操作25个钉子。每个钉子的操作包括四个阶段：选择、运输、插入和返回。本研究的目的是比较多发性硬化症（MS）患者与年龄和性别匹配的健康成年人在操作每个钉子的四个阶段所花费的时间，以及在钉子选择和插入过程中施加在钉板上的力。比较了能够解释每组参与者钉板测试时间差异的多元回归模型，以评估钉子操作属性的相对重要性。将17名MS患者（52.2±8.3岁）的表现与17名对照受试者（52.2±11.5岁）进行比较。在测力板上进行凹槽钉板测试。MS组的钉板测试时间（104±40秒）比对照组（61±15秒）长。回归分析表明，MS组的钉板测试时间可以通过钉子选择阶段的时间来预测（R = 0.78），而对照组（R = 0.77）的预测因素是钉子运输（偏相关系数r = 0.80）和选择（偏相关系数r = 0.58）阶段的时间。MS参与者完成凹槽钉板测试所需时间的差异与选择每个钉子所需的时间密切相关，而对照组的钉板测试时间主要取决于运输阶段的持续时间，但也取决于选择每个钉子的时间。
