在天然产物结构阐明中提出“如何”和“为什么”的重要性。
The importance of asking "how and why?" in natural product structure elucidation.
机构信息
EaStCHEM School of Chemistry, University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh, EH9 3FJ, UK.
出版信息
Nat Prod Rep. 2017 Oct 18;34(10):1193-1202. doi: 10.1039/c7np00025a.
Covering: up to 2017This review highlights why careful consideration of the biosynthetic origin (the how) and the biological function (the why) of a natural product can be so useful during the determination of its structure. Recent examples of structural reassignments inspired by biosynthetic and functional insights will be presented. This review will demonstrate the importance of viewing the origin, structure and function of a natural product as intertwined threads of a single story, best viewed as a whole rather than as discrete topics.
涵盖时间
截至 2017 年。本文综述了在确定天然产物结构时，仔细考虑其生物合成起源（即“如何产生”）和生物功能（即“为何具有此功能”）的重要性。本文将介绍一些受生物合成和功能见解启发的结构重分配的最新实例。该综述表明，将天然产物的起源、结构和功能视为一个整体故事中交织的线索，而不是离散的主题来进行综合考量非常重要。
Zotero 插件