Choi Won Chul, Kim Banghyun, Kim Uk, Lee Yohan, Kim Jae-Hwa
Department of Orthopaedic Surgery, CHA University, CHA Bundang Medical Center, Seongnam-si, Gyeonggi-do, Republic of Korea.
J Orthop Surg (Hong Kong). 2017 Sep-Dec;25(3):2309499017727942. doi: 10.1177/2309499017727942.
The study aim was to evaluate gap healing after medial open-wedge high tibial osteotomy (MOWHTO) using novel injectable beta-tricalcium phosphate (β-TCP) as gap filler. We also aimed to evaluate radiographic and clinical outcome of MOWHTO using injectable β-TCP.
Consecutive 28 patients underwent MOWHTO using anatomical locking plate fixation, and β-TCP was injected as gap filler. Serial radiographs and computed tomography were taken at postoperative 3 and 12 months, and gap healing was assessed. Lower extremity alignment was measured on radiographs, and clinical outcome was evaluated by determining International Knee Documentation Committee, Western Ontario and McMaster Universities Arthritis Index, and visual analogue scales for pain scores.
Progress of bone union was found on plain radiographs, and the mean ratio (β-TCP/host bone) of computed tomography attenuation values significantly changed from postoperative 3 months to 12 months, which indicates maturation of β-TCP. The average mechanical femoro-tibial angle changed from 4.1° varus (preoperative) to 4.8° valgus (3 months) and maintained until 12 months (4.3° valgus). All clinical outcome scores were significantly improved and no significant complication occurred.
Using injectable β-TCP as gap filler for MOWHTO resulted in satisfactory gap healing without complication. Radiographic and clinical results were satisfactory. The injectable β-TCP can be a safe and effective option for gap filling after MOWHTO.
本研究旨在评估采用新型可注射β-磷酸三钙(β-TCP)作为间隙填充物的内侧开放性楔形高位胫骨截骨术(MOWHTO)后的间隙愈合情况。我们还旨在评估使用可注射β-TCP的MOWHTO的影像学和临床结果。
连续28例患者接受了使用解剖锁定钢板固定的MOWHTO,并注射β-TCP作为间隙填充物。在术后3个月和12个月拍摄系列X线片和计算机断层扫描,评估间隙愈合情况。在X线片上测量下肢对线情况,并通过确定国际膝关节文献委员会、西安大略和麦克马斯特大学关节炎指数以及疼痛评分的视觉模拟量表来评估临床结果。
在平片上发现骨愈合进展,计算机断层扫描衰减值的平均比率(β-TCP/宿主骨)从术后3个月到12个月有显著变化,这表明β-TCP成熟。平均机械性股骨-胫骨角从术前的4.1°内翻变为3个月时的4.8°外翻,并维持到12个月(4.3°外翻)。所有临床结果评分均显著改善,且未发生显著并发症。
使用可注射β-TCP作为MOWHTO的间隙填充物可实现令人满意的间隙愈合且无并发症。影像学和临床结果均令人满意。可注射β-TCP可成为MOWHTO后间隙填充的一种安全有效的选择。