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沙特阿拉伯人中化脓性汗腺炎的临床模式:临床表现及治疗挑战

The Clinical Pattern of Axillary Hidradenitis Suppurativa among Saudi Arabians: Mode of Presentation and Treatment Challenges.

作者信息

Shirah Bader Hamza, Shirah Hamza Asaad

机构信息

King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.

Department of General Surgery, Al Ansar General Hospital, Medina, Saudi Arabia.

出版信息

J Cutan Aesthet Surg. 2017 Apr-Jun;10(2):95-100. doi: 10.4103/JCAS.JCAS_80_16.

Abstract

BACKGROUND

Hidradenitis suppurativa is a chronic follicular occlusive disease affecting the folliculopilosebaceous unit. The clinical course is variable, ranging from mild to severe cases. Definitive evidence-based guidelines for the management are lacking. In addition, the multifaceted clinical features and the unpredictable course of the disease make a uniform approach to treatment impractical. As a result, there are multiple therapeutic approaches. Therefore, in this study, we aim to analyze the results of management of axillary hidradenitis suppurativa among the local community in Saudi Arabia.

MATERIALS AND METHODS

A retrospective cohort database analysis of 1369 patients diagnosed and treated for axillary hidradenitis suppurativa between January 2004 and December 2013 was done. Seven hundred and forty-one (54.12%) were females and 628 (45.87%) were males. All patients with Stage I disease favored the conservative method while all patients with Stage II chose the surgical approach.

RESULTS

The mean age was 25.5 years. Nine hundred and seventy-four (71.15%) patients were treated conservatively; the mean healing time was 5.5 weeks. Three hundred and ninety-five (28.85%) patients were treated surgically. One hundred and fourteen (28.9%) had incision and drainage, 281 (71.1%) had complete excision; all wounds eventually healed without significant scarring. The recurrence rate was 12.5% (122 patients) in the conservative method group and zero (0%) in the surgical method group.

CONCLUSIONS

Hidradenitis suppurativa remains a challenging clinical condition for patients and physicians. Further studies need to focus not only on the etiology of this disease but also on the optimal treatment regimen. Public awareness programs are necessary to avoid late presentation and complications.

摘要

背景

化脓性汗腺炎是一种影响毛囊皮脂腺单位的慢性毛囊闭塞性疾病。其临床病程多变,从轻度到重度病例都有。目前缺乏基于确凿证据的管理指南。此外,该疾病多方面的临床特征和不可预测的病程使得采用统一的治疗方法不切实际。因此,存在多种治疗方法。所以,在本研究中,我们旨在分析沙特阿拉伯当地社区中腋窝化脓性汗腺炎的治疗结果。

材料与方法

对2004年1月至2013年12月期间诊断并治疗腋窝化脓性汗腺炎的1369例患者进行回顾性队列数据库分析。其中741例(54.12%)为女性,628例(45.87%)为男性。所有I期疾病患者倾向于保守治疗方法,而所有II期患者选择手术治疗方法。

结果

平均年龄为25.5岁。974例(71.15%)患者接受保守治疗;平均愈合时间为5.5周。395例(28.85%)患者接受手术治疗。114例(28.9%)进行切开引流,281例(71.1%)进行完整切除;所有伤口最终均愈合,且无明显瘢痕形成。保守治疗组的复发率为12.5%(122例患者),手术治疗组的复发率为零(0%)。

结论

化脓性汗腺炎对患者和医生来说仍然是一种具有挑战性的临床病症。进一步的研究不仅需要关注该疾病的病因,还需要关注最佳治疗方案。开展公众宣传项目对于避免疾病的延迟就诊和并发症是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a119/5561718/20dfc5112cf2/JCAS-10-95-g003.jpg

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