Burke R K
Int J Fertil. 1987 May-Jun;32(3):213-6.
Although the beneficial effect of varicocelectomy on subsequent fertility rates in subfertile men with varicocele is well documented, the effect of the dysfunction on spermatozoal fertilizing capability in this disorder remains unclear. This prospective study was conducted to determine whether sperm velocity and other quantitative semen parameters in the fresh ejaculate and after washing correlate with subsequent fertility. The authors investigated semen characteristics in 25 men with varicoceles, before and 6 months after varicocelectomy. A significant (P less than .01) correlation was observed between postvaricocelectomy improvement in sperm velocity in the fresh ejaculate and fertility. A significantly higher correlation (P less than .001) was observed between varicocele repair and improved velocity in washed, incubated sperm. No pregnancies occurred in the wives of men whose postwash sperm velocity failed to improve following surgery. It is suggested that varicocelectomy may enhance or restore the ability of spermatozoa to undergo capacitation. One may conclude that sperm velocity correlates significantly with future fertility, and that the velocity of washed, incubated sperm is the more specifically predictive evaluative measure of fertilizing capability in males who have undergone varicocele repair.
尽管精索静脉曲张切除术对患有精索静脉曲张的不育男性随后的生育率的有益影响已有充分记录，但这种功能障碍对该疾病中精子受精能力的影响仍不清楚。进行这项前瞻性研究是为了确定新鲜精液及洗涤后的精子速度和其他定量精液参数是否与随后的生育能力相关。作者调查了25名患有精索静脉曲张的男性在精索静脉曲张切除术前和术后6个月的精液特征。观察到精索静脉曲张切除术后新鲜精液中精子速度的改善与生育能力之间存在显著相关性（P小于0.01）。在精索静脉曲张修复与洗涤、孵育后的精子速度提高之间观察到显著更高的相关性（P小于0.001）。术后洗涤后精子速度未改善的男性的妻子未发生妊娠。提示精索静脉曲张切除术可能增强或恢复精子获能的能力。可以得出结论，精子速度与未来生育能力显著相关，并且洗涤、孵育后的精子速度是接受精索静脉曲张修复术男性受精能力更具特异性的预测评估指标。
