精索静脉曲张切除术对亚临床精索静脉曲张患者精子参数及妊娠率的影响：一项随机前瞻性对照研究。
Effect of varicocelectomy on sperm parameters and pregnancy rate in patients with subclinical varicocele: a randomized prospective controlled study.
作者信息
Yamamoto M, Hibi H, Hirata Y, Miyake K, Ishigaki T
机构信息
Department of Urology, Nagoya University School of Medicine, Japan.
出版信息
J Urol. 1996 May;155(5):1636-8.
PURPOSE
We assessed whether subclinical varicocele ligation improves fertility and/or semen parameters.
MATERIALS AND METHODS
A total of 85 patients with a subclinical varicocele diagnosed by scrotal thermography presented with infertility. Patients were randomly assigned to groups 1 (high ligation of the internal spermatic vein) and 2 (followed without any treatment). At least 3 semen samples were obtained at study entry and 1 year later in both groups.
RESULTS
The pregnancy rate in group 1 was 6.7% compared to 10% in group 2, and the difference was not statistically significant. Group 1 had significantly higher levels of sperm density and total motile sperm count at 1 year. There were no significant differences between groups 1 and 2 regarding change in seminal volume, sperm motility and abnormal sperm morphology.
CONCLUSIONS
Subclinical varicocelectomy has some effect on spermatogenesis but no beneficial effect on pregnancy rate.
目的
我们评估了亚临床精索静脉曲张结扎术是否能改善生育能力和/或精液参数。
材料与方法
共有85例经阴囊热成像诊断为亚临床精索静脉曲张的不育患者。患者被随机分为1组（精索内静脉高位结扎）和2组（不进行任何治疗）。两组在研究开始时和1年后均至少采集3份精液样本。
结果
1组的妊娠率为6.7%，2组为10%，差异无统计学意义。1组在1年后的精子密度和总活动精子数水平显著更高。1组和2组在精液量、精子活力和异常精子形态变化方面无显著差异。
结论
亚临床精索静脉曲张切除术对精子发生有一定影响，但对妊娠率无有益影响。
Zotero 插件