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益智药是一类单独的药物吗?各种模型中的区分。

Are nootropics a separate class of drugs? A differentiation in various models.

作者信息

Herrmann W M, Coper H

出版信息

Methods Find Exp Clin Pharmacol. 1987 Mar;9(3):173-82.

PMID:2885449
Abstract

Psychostimulants, analeptics, and nootropics are three classes of drugs that have been used with varying success in the treatment of impaired brain functions. They all produce an excitatory and disinhibitory effect on the CNS but can be distinguished through their characteristic properties. Psychostimulants are drugs that lead to a general, but nonphysiological activation, which is followed by a phase of inhibition. Analeptics are drugs that stimulate the CNS, in particular the respiratory and circulatory centers, and which in high doses lead to convulsions. Nootropics are drugs that (in impaired brain functions) lead to a physiological activation of adaptation.

摘要

精神振奋药、兴奋药和促智药是三类在治疗脑功能受损方面使用效果各异的药物。它们对中枢神经系统均产生兴奋和去抑制作用,但可通过其特性加以区分。精神振奋药会引发全身性但非生理性的激活,随后是抑制阶段。兴奋药刺激中枢神经系统,尤其是呼吸和循环中枢,高剂量时会导致惊厥。促智药(在脑功能受损时)会引发适应性的生理性激活。

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