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来自(L.)种子的银纳米颗粒对道尔顿淋巴瘤腹水(DLA)肿瘤的抗肿瘤特性数据集:简便且生物相容的方法。

Dataset on antitumor properties of silver nanoparticles from (L.) seed on Dalton Lymphoma Ascites (DLA) tumor: Facile and biocompatible approach.

作者信息

Saradhadevi Muthukirshnan, Gnanadesigan Murugesan, Kapildev Gnanajothi, Vasanth Dhakshinamoorthy

机构信息

Department of Biochemistry, Bharathiar University, Coimbatore 641046, Tamil Nadu, India.

Department of Microbial Biotechnology, Bharathiar University, Coimbatore 64106, Tamil Nadu, India.

出版信息

Data Brief. 2017 Aug 3;14:524-530. doi: 10.1016/j.dib.2017.08.003. eCollection 2017 Oct.

Abstract

The dataset depicted in this article related to our earlier article entitled "Phytofabrication and encapsulated of silver nanoparticles from " (Saradha Devi et al., 2017) [1], which reports the characteristic features (UV Visible spectra, FTIR, SEM, TEM, DLS, Zeta potential and XRD analysis) of the biosynthesised silver nanoparticles (AgNPs). In this context, the present dataset was provided to identify the antioxidant, antitumor and apoptotic (in DLA cells) properties with the synthesized AgNPs. The result enlightens the AgNPs exhibits antitumor, apoptotic activity in DLA cells and antioxidant properties. The results of the experiments increased life span of liver cells in DLA induced tumour mice and not showed any histopathological variations between control and DLA induced mice animals. The HPTLC examination of the (L.) seed extract infers the presence of colchicines derivatives as a major alkaloid sources.

摘要

本文中描述的数据集与我们之前发表的题为《从……中植物合成及包封银纳米颗粒》(萨拉达·德维等人,2017年)[1]的文章相关,该文章报道了生物合成银纳米颗粒(AgNPs)的特征(紫外可见光谱、傅里叶变换红外光谱、扫描电子显微镜、透射电子显微镜、动态光散射、zeta电位和X射线衍射分析)。在此背景下,提供本数据集以鉴定合成的AgNPs的抗氧化、抗肿瘤和凋亡(在DLA细胞中)特性。结果表明,AgNPs在DLA细胞中表现出抗肿瘤、凋亡活性以及抗氧化特性。实验结果延长了DLA诱导肿瘤小鼠的肝细胞寿命,并且在对照小鼠和DLA诱导小鼠之间未显示出任何组织病理学差异。对(L.)种子提取物的高效薄层层析检查推断,秋水仙碱衍生物作为主要生物碱来源存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01b2/5562107/598ea4503a92/gr1.jpg

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