Pawłowska Joanna, Naorniakowska Magdalena, Liber Anna
Department of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute (CMHI), Warsaw.
Individual Specialist Medical Practice, Warsaw.
Clin Exp Hepatol. 2015 Nov;1(3):117-119. doi: 10.5114/ceh.2015.55569. Epub 2015 Nov 16.
Liver injury such as hepatomegaly, splenomegaly and various degrees of biochemical abnormalities are quite common in children with collagen vascular diseases. They may be primary or secondary, particularly due to drug therapy (drug toxicity, fatty infiltration), superadded infections, diabetes or overlap with autoimmune hepatitis.
在患有胶原血管疾病的儿童中,肝损伤如肝肿大、脾肿大和各种程度的生化异常相当常见。它们可能是原发性的,也可能是继发性的,特别是由于药物治疗(药物毒性、脂肪浸润)、叠加感染、糖尿病或与自身免疫性肝炎重叠所致。