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使用点探测器阵列对调强放射治疗技术进行质量保证的实际意义。

Practical implications for the quality assurance of modulated radiation therapy techniques using point detector arrays.

作者信息

Kantz Steffi, Troeller McDermott Almut, Söhn Matthias, Reinhardt Sabine, Belka Claus, Parodi Katia, Reiner Michael

机构信息

Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.

Department of Radiation Oncology, Beaumont Health, Royal Oak, MI, USA.

出版信息

J Appl Clin Med Phys. 2017 Nov;18(6):20-31. doi: 10.1002/acm2.12157. Epub 2017 Aug 30.

Abstract

PURPOSE

Linac parameters potentially influencing the delivery quality of IMRT and VMAT plans are investigated with respect to threshold ranges, consequently to be considered in a linac based quality assurance procedure. Three commercially available 2D arrays are used to further investigate the influence of the measurement device.

METHODS

Using three commercially available 2D arrays (Mx: MatriXX , Oc: Octavius , Mc: MapCHECK2), simple static measurements, measurements for MLC characterization and dynamic interplay of gantry movement, MLC movement and variable dose rate were performed. The results were evaluated with respect to each single array as well as among each other.

RESULTS

Simple static measurements showed different array responses to dose, dose rate and profile homogeneity and revealed instabilities in dose delivery and profile shape during linac ramp up. Using the sweeping gap test, all arrays were able to detect small leaf misalignments down to ±0.1 mm, but this test also demonstrated up to 15% dose deviation due to profile instabilities and fast accelerating leaves during linac ramp up. Tests including gantry rotation showed different stability of gantry mounts for each array. Including gantry movement and dose rate variability, differences compared to static delivery were smaller compared to dose differences when simultaneously controling interplay of gantry movement, leaf movement and dose rate variability.

CONCLUSION

Linac based QA is feasible with the tested commercially available 2D arrays. Limitations of each array and the linac ramp up characteristics should be carefully considered during individual plan generation and regularly checked in linac QA. Especially the dose and dose profile during linac ramp up should be checked regularly, as well as MLC positioning accuracy using a sweeping gap test. Additionally, dynamic interplay tests including various gantry rotation speeds and angles, various leaf speeds and various dose rates should be included.

摘要

目的

针对阈值范围研究可能影响调强放疗(IMRT)和容积旋转调强放疗(VMAT)计划剂量传递质量的直线加速器参数,以便在基于直线加速器的质量保证程序中加以考虑。使用三种商用二维阵列进一步研究测量设备的影响。

方法

使用三种商用二维阵列(Mx:MatriXX、Oc:Octavius、Mc:MapCHECK2)进行简单静态测量、多叶准直器(MLC)特性测量以及机架运动、MLC运动和可变剂量率的动态相互作用测量。对每个阵列的结果以及相互之间的结果进行评估。

结果

简单静态测量显示不同阵列对剂量、剂量率和剂量分布均匀性有不同响应,并揭示了直线加速器加速过程中剂量传递和剂量分布形状的不稳定性。使用扫描间隙测试,所有阵列都能够检测到低至±0.1毫米的小叶错位,但该测试也表明,由于直线加速器加速过程中的剂量分布不稳定性和快速加速叶片,剂量偏差高达15%。包括机架旋转的测试显示每个阵列的机架安装稳定性不同。包括机架运动和剂量率变化,与静态传递相比的差异小于同时控制机架运动、叶片运动和剂量率变化时的剂量差异。

结论

使用测试的商用二维阵列进行基于直线加速器的质量保证是可行的。在制定个体计划时应仔细考虑每个阵列的局限性和直线加速器的加速特性,并在直线加速器质量保证中定期检查。特别是应定期检查直线加速器加速过程中的剂量和剂量分布,以及使用扫描间隙测试检查MLC定位精度。此外,应包括各种机架旋转速度和角度、各种叶片速度和各种剂量率的动态相互作用测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7038/5689906/b01e27ea421e/ACM2-18-020-g001.jpg

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