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4 岁患有未诊断的脾错位的暴发性甲型流感嗜血杆菌感染。

Fulminant Haemophilus Influenzae Type a Infection in a 4-year-old with Previously Undiagnosed Asplenic Heterotaxy.

机构信息

From the Department of Pediatrics, Global Child Health Residency Program, Baylor College of Medicine, Houston, Texas, Division of Hospital Medicine, Department of Pediatrics, University of Alabama at Birmingham, and Division of Infectious Disease, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.

出版信息

Pediatr Infect Dis J. 2018 Apr;37(4):e108-e110. doi: 10.1097/INF.0000000000001758.

DOI:10.1097/INF.0000000000001758
PMID:28858039
Abstract

The post Hib-vaccine era has resulted in increased cases of invasive, non-Hib, Haemophilus influenzae infections. One of the encapsulated species, type a, displays the most similarity in virulence to type b. Our patient, a fully vaccinated 4-year-old female, with newly diagnosed asplenia in the setting of heterotaxy, had a prolonged hospital course with disseminated Haemophilus influenzae type a infection.

摘要

疫苗时代后 Hib 导致侵袭性非 Hib 流感嗜血杆菌感染增加。其中荚膜型 a 与型 b 具有最相似的毒力。我们的患者是一名完全接种疫苗的 4 岁女性,伴有异构性脾切除术后,发生播散性 Haemophilus influenzae type a 感染,病程迁延。

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Two cases of type-a meningitis within the same week in the same hospital are phylogenetically unrelated but recently exchanged capsule genes.同一医院同一周内发生两例 A 型脑膜炎,两者在系统进化上无关联,但最近发生了荚膜基因交换。
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Case report of congenital asplenia presenting with Haemophilus influenzae type a (Hia) sepsis: an emerging pediatric infection in Minnesota.
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