From the Department of Pediatrics, Global Child Health Residency Program, Baylor College of Medicine, Houston, Texas, Division of Hospital Medicine, Department of Pediatrics, University of Alabama at Birmingham, and Division of Infectious Disease, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.
Pediatr Infect Dis J. 2018 Apr;37(4):e108-e110. doi: 10.1097/INF.0000000000001758.
The post Hib-vaccine era has resulted in increased cases of invasive, non-Hib, Haemophilus influenzae infections. One of the encapsulated species, type a, displays the most similarity in virulence to type b. Our patient, a fully vaccinated 4-year-old female, with newly diagnosed asplenia in the setting of heterotaxy, had a prolonged hospital course with disseminated Haemophilus influenzae type a infection.
疫苗时代后 Hib 导致侵袭性非 Hib 流感嗜血杆菌感染增加。其中荚膜型 a 与型 b 具有最相似的毒力。我们的患者是一名完全接种疫苗的 4 岁女性,伴有异构性脾切除术后,发生播散性 Haemophilus influenzae type a 感染,病程迁延。