对感染了弗氏白血病病毒的脾细胞进行抗体依赖性细胞介导的细胞毒性的扫描电子显微镜观察。
Scanning electron microscopy of antibody-dependent cell-mediated cytotoxicity of Friend leukemia virus-infected spleen cells.
作者信息
Farber P A, Friedman H
出版信息
Experientia. 1979 Jun 15;35(6):832-3. doi: 10.1007/BF01968280.
PMID:288583
Abstract
Friend leukemia virus (FLV) infected splenocytes treated with rabbit anti-FLV serum and subsequently incubated with splenic lymphocytes from non-immune Balb/c mice were examined by scanning electron microscopy. Villous-covered lymphocytes adherred to the tumor cells and induced surface blebs, numerous membrane pores and eventual tumor cell lysis.
摘要
用兔抗Friend白血病病毒（FLV）血清处理感染了FLV的脾细胞，随后与来自非免疫Balb/c小鼠的脾淋巴细胞一起孵育，通过扫描电子显微镜对这些细胞进行检查。有绒毛覆盖的淋巴细胞附着于肿瘤细胞，并诱导其表面形成泡状突起、大量膜孔，最终导致肿瘤细胞裂解。
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