Yurchenko Anna, Golovteev Alexander, Kopachev Dmitry, Dragoy Olga
National Research University Higher School of Economics, Moscow, Russia.
Epilepsy Center, Moscow, Russia.
Epilepsy Behav. 2017 Oct;75:127-133. doi: 10.1016/j.yebeh.2017.07.006. Epub 2017 Sep 15.
Previous research on linguistic performance at the single-word level in patients with temporal lobe epilepsy (TLE) has mostly been limited to the comprehension and production of nouns, and findings have been inconsistent. Results are likewise limited and controversial regarding the lateralization of the epileptogenic focus. The present study investigates comprehension and production of nouns and verbs in patients with left and right TLE (12 in each group). We designed a comprehension (word-picture matching) test and a production (naming) test, matched on a range of psycholinguistic parameters for the two word classes. The results showed impaired verb comprehension in patients with left TLE and impaired noun and verb production in both groups of patients compared to the control group. Patients with left and right TLE differed significantly on verb comprehension and noun production, whereas verb production was equally impaired in the two groups of patients. These findings suggest difficulties with single-word processing in patients with both left and right TLE, which are more prominent for verbs than for nouns in patients with left TLE. The verb production (action naming) test turned out to be the most effective tool for assessing linguistic difficulties at the single-word level in patients with TLE.
以往关于颞叶癫痫（TLE）患者单字水平语言表现的研究大多局限于名词的理解和生成，且研究结果并不一致。关于致痫灶的定位，研究结果同样有限且存在争议。本研究调查了左、右颞叶癫痫患者（每组12例）对名词和动词的理解与生成情况。我们设计了一个理解（单词-图片匹配）测试和一个生成（命名）测试，并针对这两类词在一系列心理语言学参数上进行了匹配。结果显示，与对照组相比，左颞叶癫痫患者存在动词理解障碍，两组患者均存在名词和动词生成障碍。左、右颞叶癫痫患者在动词理解和名词生成方面存在显著差异，而两组患者的动词生成障碍程度相当。这些发现表明，左、右颞叶癫痫患者在单字处理方面均存在困难，在左颞叶癫痫患者中，动词处理的困难比名词更为突出。动词生成（动作命名）测试被证明是评估颞叶癫痫患者单字水平语言困难的最有效工具。
