Glosser G, Donofrio N
Department of Neurology, University of Pennsylvania, USA.
Neuropsychology. 2001 Jan;15(1):39-47.
To test the claim that lesions of left anterior and middle temporal cortical structures specifically impair processing of nouns but not verbs, 56 left-hemisphere-language-dominant patients who had undergone anterior temporal lobectomy (ATL) completed tasks assessing confrontation naming of pictured objects and actions, generation of synonyms for nouns and verbs, and semantic lexical judgments about nouns and verbs. Compared with right ATL patients, left ATL patients were impaired across different tasks that assessed naming and comprehension of high-imageability as well as low-imageability nouns. These groups did not differ, however, in verb naming or comprehension on most tasks. Results are consistent with the hypothesized specialization of left temporal lobe structures for processing nouns and suggest that naming problems commonly seen after left ATL extend beyond difficulties with retrieving object names and may be related to subtle disturbances in comprehension of the meanings underlying nominal word forms.
为了验证左前颞叶和颞中皮质结构损伤会特异性损害名词处理而非动词处理这一说法，56名接受了前颞叶切除术（ATL）且以左侧半球为语言优势半球的患者完成了多项任务，这些任务用于评估对图片中物体和动作的对面对名、名词和动词的同义词生成，以及对名词和动词的语义词汇判断。与接受右侧ATL手术的患者相比，接受左侧ATL手术的患者在评估高形象性和低形象性名词命名及理解的不同任务中均表现受损。然而，在大多数任务中，这两组患者在动词命名或理解方面并无差异。研究结果与左颞叶结构在处理名词方面的假设特化相一致，并表明左ATL术后常见的命名问题不仅限于检索物体名称困难，可能还与对名词词形背后含义理解的细微干扰有关。
