Department of Microbiology, Tokushima University Graduate School of Medical Science, Tokushima 770-8503, Japan.
Department of Microbiology, Tokushima University Graduate School of Medical Science, Tokushima 770-8503, Japan; Department of Microbiology, Kansai Medical University, Osaka 573-1010, Japan.
Microbes Infect. 2018 Oct-Nov;20(9-10):610-614. doi: 10.1016/j.micinf.2017.08.003. Epub 2017 Aug 30.
Human immunodeficiency virus type 1 (HIV-1) is specifically adapted for replication, persistence, transmission, and survival in humans. HIV-1 is highly mutable in nature, and well responds to a variety of environmental pressures by altering its genome sequences. In this review, we have described experimental evidence that demonstrates this phantasmagoric property of HIV-1.
人类免疫缺陷病毒 1 型(HIV-1)是专门为在人类中进行复制、持续存在、传播和存活而适应的。HIV-1 在自然界中具有高度的可变性,通过改变其基因组序列,很好地应对了各种环境压力。在这篇综述中,我们描述了实验证据,证明了 HIV-1 的这种奇幻特性。