Okubo Rieko, Ito Kimihiko, Nakatsuka Shinichi, Watanabe Hitoshi, Yagi Taro, Odani Chihiro, Ono Hitomi, Shimoji Kanoko, Nakagawa Mio, Goto Mayako, Tsuruta Tomohiko, Hori Kensuke, Tashima Lena
Dept. of Obstetrics and Gynecology, Kansai Rosai Hospital.
Gan To Kagaku Ryoho. 2017 Aug;44(8):681-684.
The incidence of lymph node metastasis in pT1 epithelial ovarian cancer is between 5% and 21%. Most cases with lymph node metastasis are those of serous carcinoma; it is relatively rare in mucinous carcinoma. Therefore, there is a recent trend to omit systematic lymphadenectomy in early stage mucinous carcinoma. The purpose of this study was to verify whether the omission of systematic lymphadenectomy in mucinous carcinoma is oncologically safe.
We reviewed all pT1 epithelial ovarian cancer cases that were treated in our hospital between January 2002 and December 2015.
Fiftynine cases of pT1 epithelial ovarian cancer were included. The overall rate of lymph node metastasis was 6.8%(4 in 59). It was 6.5%(2 in 31)in clear cell carcinoma and 22.2%(2 in 9)in mucinous carcinoma.
According to our study, lymph node metastasis in pT1 mucinous carcinoma has a rate of 22.2% and some affected cases were not detected by presurgery imaging studies. Therefore, we need to be careful about the omission of systematic lymphadenectomy in mucinous carcinoma.
pT1期上皮性卵巢癌的淋巴结转移发生率在5%至21%之间。大多数发生淋巴结转移的病例为浆液性癌；在黏液性癌中相对少见。因此，近期存在一种在早期黏液性癌中省略系统性淋巴结清扫术的趋势。本研究的目的是验证在黏液性癌中省略系统性淋巴结清扫术在肿瘤学上是否安全。
我们回顾了2002年1月至2015年12月在我院接受治疗的所有pT1期上皮性卵巢癌病例。
纳入59例pT1期上皮性卵巢癌病例。淋巴结转移的总体发生率为6.8%（59例中有4例）。透明细胞癌为6.5%（31例中有2例），黏液性癌为22.2%（9例中有2例）。
根据我们的研究，pT1期黏液性癌的淋巴结转移率为22.2%，且一些受累病例术前影像学检查未检测到。因此，在黏液性癌中省略系统性淋巴结清扫术时我们需要谨慎。
