Li Wenzhen, Wang Dongming, Wu Chunmei, Shi Oumin, Zhou Yanfeng, Lu Zuxun
Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sci Rep. 2017 Aug 31;7(1):10256. doi: 10.1038/s41598-017-11037-y.
Few studies have been conducted to explore the independent and combined associations of body mass index (BMI) and physical activity with risk of hypertension in Chinese population. A cross-sectional study of 5291 individuals (aged ≥ 40 years) selected using multi-stage sampling method was conducted from October 2013 to December 2015. In the present analysis, 55.64% of the participants were women, and the mean age of participants was 55.37 ± 10.56. Compared with individuals in normal group, the risks of hypertension were nearly double in overweight subjects (odds ratio [OR] 1.77, 95% confidence interval [CI] 1.53-2.05) and more than three times higher in obese subjects (3.23, 2.62-4.13). Multi-adjusted odds for hypertension associated with low, moderate, and high physical activity were 1.44 (1.17-1.86), 1.40 (1.09-1.79) and 1.000, respectively. In comparison with normal weight subjects who reported high levels of physical activity, subjects who reported both low levels of physical activity and obesity showed the highest risk of hypertension (5.89, 3.90-8.88). In conclusion, both elevated BMI and reduced physical activity appear to play an important role in the risk of hypertension among Chinese middle-aged and older population. The risk of hypertension associated with overweight and obesity can be reduced considerably by increased physical activity levels.
很少有研究探讨体重指数（BMI）和身体活动与中国人群高血压风险之间的独立关联和联合关联。2013年10月至2015年12月，采用多阶段抽样方法对5291名年龄≥40岁的个体进行了一项横断面研究。在本分析中，55.64%的参与者为女性，参与者的平均年龄为55.37±10.56岁。与正常组个体相比，超重受试者患高血压的风险几乎翻倍（优势比[OR]1.77，95%置信区间[CI]1.53 - 2.05），肥胖受试者患高血压的风险则高出三倍多（3.23，2.62 - 4.13）。与低、中、高身体活动相关的高血压多因素调整优势比分别为1.44（1.17 - 1.86）、1.40（1.09 - 1.79）和1.000。与报告高水平身体活动的正常体重受试者相比，报告低水平身体活动且肥胖的受试者患高血压的风险最高（5.89，3.90 - 8.88）。总之，BMI升高和身体活动减少似乎在中国中老年人群高血压风险中都起着重要作用。通过增加身体活动水平，与超重和肥胖相关的高血压风险可大幅降低。
