Huang Juncheng, Bin Abd Razak Hamid Rahmatullah, Yeo Seng Jin
Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
Ann Transl Med. 2017 Aug;5(16):321. doi: 10.21037/atm.2017.06.40.
Very little is known in the literature with regards to the incidence of postoperative delirium following total knee arthroplasty (TKA) in Asians and the associated surgical factors. We conducted a retrospective study on incidence of postoperative delirium following TKA in Asians.
One thousand sixteen knees of 954 consecutive patients who underwent TKA by the senior author of this study in the year 2006 were included in this review. All written and electronic medical records for patients were screened. Delirium was recorded to be present based on clinical entry onto the patients' inpatient hospital notes and a diagnosis made by psychiatrist based on the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV). All statistical analysis was performed using SPSS v.18.0 (IBM Corp., Armonk, NY, USA).
The incidence of postoperative delirium in our patients undergoing TKA was 0.59%. Six patients had a confirmed diagnosis of delirium postoperatively. We noted an association between a higher mean age (P<0.0001), a lower body mass index (P<0.0001), Chinese ethnicity (P=0.002), male gender (P=0.002) and chronic opioid use (P<0.0001) with incidence of post-operative delirium. We also noted a higher proportion of post-operative DVT (P<0.0001) and wound infection (P<0.0001) in the delirium group.
The incidence of postoperative delirium in Asians undergoing TKA in our institution is very low at 0.59%. Advanced age, lower body mass index, Chinese ethnicity, male gender and preoperative chronic opioid use may be associated with developing postoperative delirium.
关于亚洲人全膝关节置换术(TKA)后谵妄的发生率及相关手术因素,文献中所知甚少。我们对亚洲人TKA术后谵妄的发生率进行了一项回顾性研究。
本回顾性研究纳入了2006年由本研究的资深作者为954例连续患者实施的1016例TKA手术。对患者所有的书面和电子病历进行筛查。根据患者住院病历中的临床记录以及精神科医生依据《精神疾病诊断与统计手册》第4版(DSM-IV)做出的诊断,记录谵妄的存在情况。所有统计分析均使用SPSS v.18.0(美国纽约州阿蒙克市IBM公司)进行。
我们的TKA患者术后谵妄的发生率为0.59%。6例患者术后确诊为谵妄。我们注意到较高的平均年龄(P<0.0001)、较低的体重指数(P<0.0001)、华裔(P=0.002)、男性(P=0.002)和长期使用阿片类药物(P<0.0001)与术后谵妄的发生率相关。我们还注意到谵妄组术后深静脉血栓形成(DVT)(P<0.0001)和伤口感染(P<0.0001)的比例更高。
在我们机构中,亚洲人TKA术后谵妄的发生率非常低,为0.59%。高龄、低体重指数、华裔、男性以及术前长期使用阿片类药物可能与术后谵妄的发生有关。