一种基于目标诱导分裂型脱氧核酶片段结合的具有级联信号放大功能的用于汞监测的裸眼比色传感器。
A naked-eye colorimetric sensor for Hg monitoring with cascade signal amplification based on target-induced conjunction of split DNAzyme fragments.
作者信息
Chen Junhua, Pan Jiafeng, Chen Shu
机构信息
Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and Management, Guangdong Institute of Eco-environmental Science & Technology, Guangzhou 510650, China.
出版信息
Chem Commun (Camb). 2017 Sep 12;53(73):10224-10227. doi: 10.1039/c7cc05445a.
PMID:28861569
Abstract
A colorimetric sensor for the visual detection of Hg with cascade signal amplification has been successfully constructed using split DNAzyme subunits as sensing elements and gold nanoparticles as signal reporters. The biosensor is ultrasensitive, enabling the visual detection of trace levels of Hg as low as 10 pM without instrumentation.
摘要
一种用于可视化检测汞的比色传感器已成功构建，该传感器使用分裂的脱氧核酶亚基作为传感元件，金纳米颗粒作为信号报告分子，具有级联信号放大功能。这种生物传感器具有超高灵敏度，无需仪器即可实现对低至10皮摩尔的痕量汞进行可视化检测。
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