1Department of Neurology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University,Hangzhou,China.
2Department of Neurology,Ningbo No. 2 Hospital,Ningbo,China.
Can J Neurol Sci. 2017 Sep;44(5):556-561. doi: 10.1017/cjn.2017.202.
This study assesses the value of the video head impulse test (vHIT) for early diagnosis of vestibular neuritis (VN) among acute vertigo.
Thirty-three cases of vestibular neuritis (VN), 96 patients with other acute vertigo (AV), and 50 cases of normal controls used vHIT to quantitatively test a pair of horizontal vestibulo-ocular reflection (VOR) gains, two pairs of vertical VOR gains, and the corresponding three pairs of VOR gain asymmetry. The peculiarity of VOR gains in VN and the differences between VN and other AV, normal controls by vHIT, were collected and analyzed.
There were statistically significant differences in the three pairs of VOR gains asymmetry between VN and other AV, and normal controls (P<0.01). The sensitivity was 87.9% and specificity was 94.3% in differentiating VN from normal and other acute vertigo by vHIT.
This study shows vHIT has advantages in the diagnosis of VN in acute vertigo with good sensitivity and specificity and indicates a widespread clinical application.
本研究评估视频头脉冲试验（vHIT）在急性眩晕患者中早期诊断前庭神经炎（VN）的价值。
33 例前庭神经炎（VN）患者、96 例其他急性眩晕（AV）患者和 50 例正常对照者采用 vHIT 定量检测一对水平前庭眼反射（VOR）增益、两对垂直 VOR 增益和相应的三对 VOR 增益不对称性。收集并分析 VN 与其他 AV、正常对照者 vHIT 中 VOR 增益的特点及差异。
VN 与其他 AV、正常对照组的三对 VOR 增益不对称性差异有统计学意义（P<0.01）。vHIT 鉴别 VN 与正常和其他急性眩晕的敏感性为 87.9%，特异性为 94.3%。
本研究表明 vHIT 在急性眩晕中诊断 VN 具有良好的敏感性和特异性，具有广泛的临床应用价值。
