• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Heterologous expression of porcine elongase 6 () gene in a human cell line.

作者信息

Gupta Saurabh, Santra Lakshman, Naskar Soumen, Maurya Sanjeev K, Rana Mashidur, Ghosh Jyotirmoy, Dhara Sujoy K

机构信息

Stem Cell Laboratory, Division of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute, Bareilly, Uttar Pradesh, India.

School of Genomics and Molecular Breeding, ICAR-Indian Institute of Agricultural Biotechnology, Ranchi, Jharkhand, India.

出版信息

Indian J Med Res. 2017 Apr;145(4):563-568. doi: 10.4103/ijmr.IJMR_785_16.

DOI:10.4103/ijmr.IJMR_785_16
PMID:28862191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5663173/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/1b820ef42ef6/IJMR-145-563-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/91a51d307c60/IJMR-145-563-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/2d54c7f58511/IJMR-145-563-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/1b820ef42ef6/IJMR-145-563-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/91a51d307c60/IJMR-145-563-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/2d54c7f58511/IJMR-145-563-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fc/5663173/1b820ef42ef6/IJMR-145-563-g003.jpg

相似文献

1
Heterologous expression of porcine elongase 6 () gene in a human cell line.猪延长酶6（）基因在人细胞系中的异源表达。 （注：原文中“elongase 6 ()”括号内内容缺失）
Indian J Med Res. 2017 Apr;145(4):563-568. doi: 10.4103/ijmr.IJMR_785_16.
2
Molecular characterization of elongase of very long-chain fatty acids 6 (elovl6) genes in Misgurnus anguillicaudatus and their potential roles in adaptation to cold temperature.泥鳅 elongase of very long-chain fatty acids 6 (elovl6) 基因的分子特征及其在适应低温中的潜在作用。
Gene. 2018 Aug 5;666:134-144. doi: 10.1016/j.gene.2018.05.019. Epub 2018 May 5.
3
Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity.在小鼠中敲除长链脂肪酸延长酶 ELOVL3 会导致脂质储存受限和抵抗饮食诱导的肥胖。
FASEB J. 2010 Nov;24(11):4366-77. doi: 10.1096/fj.09-152298. Epub 2010 Jul 6.
4
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.长链脂肪酸延长酶Elovl6在肥胖诱导的胰岛素抵抗中的关键作用。
Nat Med. 2007 Oct;13(10):1193-202. doi: 10.1038/nm1662. Epub 2007 Sep 30.
5
Hepatic ELOVL6 mRNA is regulated by the gga-miR-22-3p in egg-laying hen.产蛋母鸡肝脏中的ELOVL6 mRNA受gga-miR-22-3p调控。
Gene. 2017 Aug 5;623:72-79. doi: 10.1016/j.gene.2017.04.040. Epub 2017 Apr 23.
6
Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.硬脂酰辅酶 A 去饱和酶和 Elovl6 对棕榈酸诱导的胰岛β细胞内质网应激和凋亡的调节作用。
Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E640-9. doi: 10.1152/ajpendo.00544.2010. Epub 2011 Jan 25.
7
Genetic variants of fatty acid elongase 6 in Chinese Holstein cow.中国荷斯坦奶牛脂肪酸延长酶 6 的遗传变异。
Gene. 2018 Sep 5;670:123-129. doi: 10.1016/j.gene.2018.05.073. Epub 2018 May 19.
8
Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake.小鼠中人类肝脂肪酶的过表达通过促进肝脏脂肪生成、白色脂肪组织脂肪分解和脂肪酸摄取，诱导肝脂肪变性和肥胖。
PLoS One. 2017 Dec 15;12(12):e0189834. doi: 10.1371/journal.pone.0189834. eCollection 2017.
9
Tissue expression profiles and transcriptional regulation of elongase of very long chain fatty acid 6 in bovine mammary epithelial cells.牛乳腺上皮细胞中极长链脂肪酸延长酶6的组织表达谱及转录调控
PLoS One. 2017 Apr 17;12(4):e0175777. doi: 10.1371/journal.pone.0175777. eCollection 2017.
10
Isolation and functional characterization of fatty acid delta5-elongase gene from the liverwort Marchantia polymorpha L.地钱脂肪酸δ5-延长酶基因的分离与功能鉴定
FEBS Lett. 2006 Jan 9;580(1):149-54. doi: 10.1016/j.febslet.2005.11.065. Epub 2005 Dec 6.

引用本文的文献

1
Decreased expression levels of ELOVL6 indicate poor prognosis in hepatocellular carcinoma.ELOVL6表达水平降低表明肝细胞癌预后不良。
Oncol Lett. 2019 Dec;18(6):6214-6220. doi: 10.3892/ol.2019.10974. Epub 2019 Oct 9.

本文引用的文献

1
The production of multi-transgenic pigs: update and perspectives for xenotransplantation.多转基因猪的生产：异种移植的最新进展与展望
Transgenic Res. 2016 Jun;25(3):361-74. doi: 10.1007/s11248-016-9934-8. Epub 2016 Jan 28.
2
Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.ELOVL6基因的缺失会阻断油酸的合成，但不会阻止脂肪肝或胰岛素抵抗的发展。
J Lipid Res. 2014 Dec;55(12):2597-605. doi: 10.1194/jlr.M054353. Epub 2014 Oct 3.
3
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations.
人胚肾293细胞系在细胞生物学操作下的基因组动态变化
Nat Commun. 2014 Sep 3;5:4767. doi: 10.1038/ncomms5767.
4
Diabetes and cardiovascular disease in older adults: current status and future directions.老年人的糖尿病与心血管疾病：现状与未来方向。
Diabetes. 2014 Aug;63(8):2578-89. doi: 10.2337/db14-0020.
5
Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle.在脂肪酸延长循环中，3-酮酰基辅酶A还原酶KAR对脂肪酸延长酶ELOVL6的两种调节模式。
PLoS One. 2014 Jul 8;9(7):e101823. doi: 10.1371/journal.pone.0101823. eCollection 2014.
6
The effect of LXRα, ChREBP and Elovl6 in liver and white adipose tissue on medium- and long-chain fatty acid diet-induced insulin resistance.肝脏和白色脂肪组织中的肝X受体α（LXRα）、碳水化合物反应元件结合蛋白（ChREBP）和脂肪酸延长酶6（Elovl6）对中长链脂肪酸饮食诱导的胰岛素抵抗的影响。
Diabetes Res Clin Pract. 2013 Dec;102(3):183-92. doi: 10.1016/j.diabres.2013.10.010. Epub 2013 Oct 26.
7
Brown and beige fat: development, function and therapeutic potential.棕色和米色脂肪：发育、功能与治疗潜能。
Nat Med. 2013 Oct;19(10):1252-63. doi: 10.1038/nm.3361. Epub 2013 Sep 29.
8
Tissue and cell-specific transcriptional activity of the human cytomegalovirus immediate early gene promoter (UL123) in zebrafish.人巨细胞病毒立即早期基因启动子（UL123）在斑马鱼中的组织和细胞特异性转录活性
Gene Expr Patterns. 2013 Mar-Apr;13(3-4):91-103. doi: 10.1016/j.gep.2013.01.003. Epub 2013 Jan 22.
9
Human mesenchymal stem cells derived from limb bud can differentiate into all three embryonic germ layers lineages.源自肢芽的人间充质干细胞可分化为所有三个胚胎胚层谱系。
Cell Reprogram. 2012 Aug;14(4):324-33. doi: 10.1089/cell.2012.0004. Epub 2012 Jul 9.
10
Influence of codon bias on heterologous production of human papillomavirus type 16 major structural protein L1 in yeast.密码子偏性对人乳头瘤病毒16型主要结构蛋白L1在酵母中异源表达的影响
ScientificWorldJournal. 2012;2012:979218. doi: 10.1100/2012/979218. Epub 2012 May 2.