Vahedi Amir, Moya-Plana Antoine, Guyot Sylvie, Touré Gaoussou
Consultant Maxillofacial Surgeon, Service de Chirurgie Maxillofaciale, CHI, Villeneuve Saint-Georges, France.
Consultant ENT, HEGP-Paris 5 Service ORL, Paris, France.
J Oral Maxillofac Surg. 2018 Feb;76(2):363-367. doi: 10.1016/j.joms.2017.07.173. Epub 2017 Aug 5.
Plasma cell granuloma or inflammatory pseudotumor (IPT) is diagnosed by a process of elimination. The precise etiology is unknown, although it can occur after a bout of periodontal infection. This report describes the various stages of progression for this ailment. A 49-year-old woman with no noteworthy medical history presented with a recurrent periodontal abscess accompanied by progressive and severe destruction of the right maxilla. There was invasion of the infratemporal fossa and very tight trismus. Histologic examination indicated a reactive plasma cell granuloma. IPT is an entity recognized by the World Health Organization. A triggering infectious or inflammatory factor is often present. In the maxilla, progression is very aggressive. Treatment relies on corticotherapy, with or without radiotherapy, and administration of cyclosporine.
浆细胞性肉芽肿或炎性假瘤(IPT)是通过排除法诊断的。尽管它可在牙周感染发作后发生,但其确切病因尚不清楚。本报告描述了这种疾病的各个进展阶段。一名49岁无显著病史的女性出现复发性牙周脓肿,并伴有右上颌骨进行性严重破坏。存在颞下窝侵犯和严重牙关紧闭。组织学检查显示为反应性浆细胞性肉芽肿。IPT是世界卫生组织认可的一种疾病。通常存在引发感染或炎症的因素。在上颌骨中,病情进展非常迅速。治疗依靠皮质激素疗法,可联合或不联合放疗,并给予环孢素。