Fossa Shirata M M, Campos P M B G Maia
Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n - Monte Alegre, 14040-903, Ribeirão Preto, SP, Brazil.
Int J Cosmet Sci. 2017 Dec;39(6):622-628. doi: 10.1111/ics.12424. Epub 2017 Oct 13.
Considering that many cosmetic products contain UV filters in their composition and that few studies have evaluated the role of UV filters in the physical properties and clinical efficacy of these products, the aim of this study was to assess the influence of UV filters on the properties and immediate effects of a cosmetic formulation.
Four cosmetic formulations, vehicle (V), vehicle containing UV filters (F), vehicle containing cassava polysaccharides and alfalfa (A) oligosaccharides and vehicle containing UV filters plus cassava polysaccharides and alfalfa oligosaccharides (multifunctional formulation, M) were developed. The texture profile of the formulations was analysed with a TA.XT plus Texturometer . Twenty female volunteers aged 39-45 years were then selected for the assessment of immediate clinical efficacy of the formulations under study and of transepidermal water loss (TEWL), stratum corneum water content and microrelief of the skin obtained with their use.
The presence of UV filters resulted in an improvement of the physical properties of the multifunctional cosmetic formulation (M) and of skin microrelief. However, the presence of UV filters also caused a significant decrease in hydration.
The presence of sunscreens had a negative influence on immediate skin hydration and TEWL. On the other hand, it positively influenced parameters related to the physical properties of the multifunctional formulation and skin microrelief. Thus, we conclude that the influence of UV filters on the development of cosmetic formulations is an important factor to be considered because it can have either positive or negative effect on the efficacy of the product.
鉴于许多化妆品在其成分中含有紫外线过滤剂,且很少有研究评估紫外线过滤剂在这些产品的物理性质和临床功效中的作用,本研究的目的是评估紫外线过滤剂对化妆品配方的性质和即时效果的影响。
开发了四种化妆品配方,分别为基质(V)、含紫外线过滤剂的基质(F)、含木薯多糖和苜蓿(A)寡糖的基质以及含紫外线过滤剂加木薯多糖和苜蓿寡糖的多功能配方(M)。使用TA.XT plus质构仪分析配方的质地剖面。然后挑选20名年龄在39至45岁之间的女性志愿者,以评估所研究配方的即时临床功效以及使用这些配方后皮肤的经表皮水分流失(TEWL)、角质层含水量和微观纹理。
紫外线过滤剂的存在改善了多功能化妆品配方(M)的物理性质和皮肤微观纹理。然而,紫外线过滤剂的存在也导致了皮肤水合作用的显著降低。
防晒剂的存在对皮肤即时水合作用和TEWL有负面影响。另一方面,它对与多功能配方的物理性质和皮肤微观纹理相关的参数有积极影响。因此,我们得出结论,紫外线过滤剂对化妆品配方开发的影响是一个需要考虑的重要因素,因为它可能对产品功效产生正面或负面影响。