Dept. Of Psychiatry, Centre of Excellence in Mental Health, PGIMER-Dr. R.M.L. Hospital, New Delhi, India.
GRIP- NIH Project, Dept. of Psychiatry, Centre of Excellence in Mental Health, PGIMER-Dr. R.M.L. Hospital, New Delhi, India.
Asian J Psychiatr. 2017 Dec;30:102-106. doi: 10.1016/j.ajp.2017.08.012. Epub 2017 Aug 18.
The risk of suicide among persons with schizophrenia (SZ) is higher than in general population, with multiple contributory factors. We assessed the prevalence of risk of deliberate self-harm and suicide attempts, along with associated socio-demographic and clinical factors in a group of SZ outpatients (n=61) as part of a larger study on overall schizophrenia-associated risks.
To investigate factors associated with risk of deliberate self-harm and suicide among persons with schizophrenia.
Out of 270 SZ participants evaluated for various risks using Ram Manohar Lohia Risk Assessment Interview (RML-RAI), 61 reported risk of self-harm including suicide attempt/s. The factors associated with this risk were further evaluated on clinical details and Diagnostic Interview for Genetic Studies.
Risk of reported self-harm was 22.59%. Among them, 10% had attempted suicide at least once. Current age and past month Global Assessment of Functioning score from DIGS (GAF) were significantly correlated with suicide attempt. Attempters had significantly lower current GAF score, indicating poorer functioning. Among 27 attempters, 9 attempted at the onset of illness while 6 others attempted suicide within one year. Most common method of attempt was ingestion of insecticides or overdose of medication, followed by hanging or jumping from height.
In our hospital-based sample of suicide attempters, 10% had attempted suicide, among them over 55% within first year of illness. Attempters were significantly older than non-attempters and suffered from significantly more severe illness than non-attempters. Positive symptoms were significantly associated with attempt, irrespective of time at which suicide was attempted.
精神分裂症患者(SZ)自杀的风险高于一般人群,存在多种促成因素。我们评估了一组 SZ 门诊患者(n=61)故意自残和自杀企图的风险,以及与社会人口统计学和临床因素相关的风险,这是一项关于整体与精神分裂症相关风险的更大研究的一部分。
调查与精神分裂症患者故意自残和自杀风险相关的因素。
在使用 Ram Manohar Lohia 风险评估访谈 (RML-RAI) 评估 270 名 SZ 参与者的各种风险的过程中,有 61 名参与者报告了自残风险,包括自杀企图。进一步根据临床详细信息和遗传研究诊断访谈评估与这种风险相关的因素。
报告的自残风险为 22.59%。其中,10%的人至少有过一次自杀企图。目前的年龄和过去一个月来自 DIGS 的总体功能评估(GAF)评分与自杀企图显著相关。企图自杀者的当前 GAF 评分明显较低,表明功能更差。在 27 名企图自杀者中,有 9 人在发病时企图自杀,而另外 6 人在一年内企图自杀。最常见的企图自杀方法是吞食杀虫剂或过量服用药物,其次是上吊或从高处跳下。
在我们的基于医院的自杀企图者样本中,10%的人曾企图自杀,其中超过 55%的人在发病的第一年就试图自杀。企图自杀者明显比非企图自杀者年龄大,而且病情比非企图自杀者严重。阳性症状与自杀企图显著相关,与自杀发生的时间无关。