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关节镜下单步修复距骨骨软骨病变中无细胞聚合物基支架:临床和放射学结果。

Single-Step Arthroscopic Repair With Cell-Free Polymer-Based Scaffold in Osteochondral Lesions of the Talus: Clinical and Radiological Results.

机构信息

Department of Orthopedic Surgery, Gazi University Medical School, Ankara, Turkey.

Department of Orthopedic Surgery, Gazi University Medical School, Ankara, Turkey.

出版信息

Arthroscopy. 2017 Sep;33(9):1718-1726. doi: 10.1016/j.arthro.2017.06.011.

Abstract

PURPOSE

To report the clinical and radiological results of patients with talar osteochondral lesions who were treated by microfracture and cell-free scaffold implantation in a single-step arthroscopic surgery.

METHODS

Forty patients, treated with a single-step arthroscopic surgery, were evaluated in this single-center-based retrospective study. Patients with degenerative arthritis (n = 1), history of ankle fracture (n = 1), kissing lesions (n = 1), lower extremity deformity (n = 1), and lesions <1.5 cm (n = 4) were excluded. Oversized (>10 mm depth) bone cysts were additionally treated with bone graft. Patients were evaluated clinically, using the American Orthopedic Foot and Ankle Society (AOFAS) hindfoot score. Radiological assessment was performed with magnetic resonance imaging, using the magnetic resonance observation of cartilage repair tissue (MOCART) score.

RESULTS

Thirty-two patients with a mean age of 38 ± 12 years were evaluated. The mean defect size was 2.5 ± 0.8 cm and the mean defect volume was 2.4 ± 1.9 cm. The mean preoperative AOFAS score was 52.8 ± 13.9 and increased to 87.1 ± 11.1 postoperatively at the mean follow-up of 33.8 ± 14.0 months (P = .0001). A total of 84.4% of patients had good to excellent clinical scores. Clinical scores had no significant relation with age, lesion size, depth, or body mass index. The mean MOCART score was 64.2 ± 12.0. There was no significant correlation between the total MOCART and AOFAS scores (P = .123). A significant relation was found between the defect filling (the subgroup of the MOCART score) and the clinical outcomes (P = .0001, rho = 0.731).

CONCLUSIONS

The arthroscopic scaffold implantation technique is a single-step, safe, and effective method for the treatment of talar osteochondral lesions with satisfactory clinical and radiological outcomes.

LEVEL OF EVIDENCE

Level IV, therapeutic case series.

摘要

目的

报告在单步关节镜手术中通过微骨折和无细胞支架植入治疗距骨骨软骨病变患者的临床和影像学结果。

方法

在这项单中心回顾性研究中,对 40 名接受单步关节镜手术治疗的患者进行了评估。排除了退行性关节炎患者(n=1)、踝关节骨折病史患者(n=1)、吻痕病变患者(n=1)、下肢畸形患者(n=1)和病变<1.5cm 患者(n=4)。对于过大(>10mm 深度)骨囊肿,另外采用骨移植进行治疗。使用美国矫形足踝协会(AOFAS)后足评分对患者进行临床评估。使用磁共振软骨修复组织观察(MOCART)评分进行影像学评估。

结果

32 名患者的平均年龄为 38±12 岁。平均缺损大小为 2.5±0.8cm,平均缺损体积为 2.4±1.9cm。术前 AOFAS 平均评分为 52.8±13.9,术后平均随访 33.8±14.0 个月时增加至 87.1±11.1(P=.0001)。84.4%的患者临床评分良好或优秀。临床评分与年龄、病变大小、深度或体重指数无显著相关性。平均 MOCART 评分为 64.2±12.0。总 MOCART 评分与 AOFAS 评分无显著相关性(P=.123)。缺损填充(MOCART 评分亚组)与临床结果之间存在显著关系(P=.0001,rho=0.731)。

结论

关节镜下支架植入技术是一种单步、安全、有效的治疗距骨骨软骨病变的方法,具有满意的临床和影像学结果。

证据等级

IV 级,治疗性病例系列。

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