Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università degli Studi di Milano, Milan, Italy; IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università degli Studi di Milano, Milan, Italy; IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
J Evid Based Dent Pract. 2017 Sep;17(3):239-255. doi: 10.1016/j.jebdp.2017.04.006. Epub 2017 Apr 23.
Evaluation of the methodological quality of systematic reviews (SRs) on the effectiveness of autologous platelet concentrates as an adjunct to regenerative procedures for the treatment of periodontal defects.
After a literature screening, eligible SRs were qualitatively assessed using 2 validated instruments: A Measurement Tool to Assess systematic Reviews checklist and Overview Quality Assessment Questionnaire. The characteristics and findings of SRs were also reported.
Ten SRs fulfilled the inclusion criteria and were evaluated. With A MeaSurement Tool to Assess systematic Reviews tool, SRs displayed a generally satisfying quality. Six SRs satisfied ≥8 items of 11 (high-quality score), and 4 were classified of medium quality (score 4-7). Using Overview Quality Assessment Questionnaire instrument, more than half SRs (N = 6) satisfied ≥7 items of 9, resulting to be of high quality; 3 were classified as medium quality (4-6 criteria met); and only 1 of low quality (3 items satisfied). A significant correlation between the results of the 2 questionnaires was found (Spearman's r = 0.915, P = .0005).
SRs considered had an overall high methodological quality. However, some areas were not systematically addressed, like a thorough research strategy or publication bias assessment. Standard guidelines for designing, performing, and reporting SRs should always be followed. The use of platelet concentrates as an adjunct to periodontal surgery procedures may have beneficial effects for the treatment of periodontal defects.
评估关于自体血小板浓缩物作为再生程序辅助治疗牙周缺损的有效性的系统评价（SR）的方法学质量。
经过文献筛选，使用 2 种经过验证的工具对合格的 SR 进行定性评估：评估系统评价的测量工具清单和概述质量评估问卷。还报告了 SR 的特征和发现。
10 篇 SR 符合纳入标准并进行了评估。使用评估系统评价的测量工具，SR 显示出总体令人满意的质量。6 篇 SR 满足 11 项中的≥8 项（高质量评分），4 篇被归类为中等质量（评分 4-7）。使用概述质量评估问卷工具，超过一半的 SR（N=6）满足 9 项中的≥7 项，被评为高质量；3 篇被归类为中等质量（满足 4-6 项标准）；只有 1 篇为低质量（满足 3 项标准）。这两种问卷的结果之间存在显著相关性（Spearman r=0.915，P=.0005）。
考虑到的 SR 具有总体较高的方法学质量。然而，一些领域并未得到系统解决，例如彻底的研究策略或发表偏倚评估。应始终遵循设计、执行和报告 SR 的标准指南。将血小板浓缩物作为牙周手术程序的辅助物可能对治疗牙周缺损具有有益效果。
