Chiesa Estomba Carlos Miguel, González García Jose Angel, Sistiaga Suarez Jon Alexander, Thomas Arrizabalaga Izaskun, Larruscain Sarasola Ekhiñe, Altuna Mariezcurrena Xabier
Servicio de Otorrinolaringología-Cirugía de Cabeza y Cuello, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España.
Servicio de Otorrinolaringología-Cirugía de Cabeza y Cuello, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España.
Acta Otorrinolaringol Esp (Engl Ed). 2018 Mar-Apr;69(2):99-104. doi: 10.1016/j.otorri.2017.06.003. Epub 2017 Sep 1.
Pharyngocutaneous fistula is the most frequent complication after total laryngectomy. Its incidence varies between 9%-25% in post primary total laryngectomy patients, to 14%-57% in salvage laryngectomy post radiotherapy or post chemotherapy + radiotherapy. The pectoralis major myofascial flap (PMMF)is postulated as a useful tool to decrease the incidence of this complication.
Retrospective analysis of a group of patients treated by salvage laryngectomy, associated or not with pharyngeal closure reinforcement with PMMF.
Twenty patients were included, 18 males (90%) and 2 females (10%), in 10 of whom the PMMF was used. The average age was 66.65 years. Seventeen (85%) had a laryngeal tumour and 3 (15%) had a hypopharyngeal tumour. Eight (80%) patients in the non-PMMF group had postoperative fistula, whereas only 2 (20%) patients in the PMMF group had a fistula during the postoperative period (P=.005). The mean time for fistula closure was significantly shorter in the cases where PMMF flap was used (16±11 days vs. 76.8±67 days, P=.001), as was hospital stay (19. 6±18 days vs. 83.9±77 days, P=.001).
The use of PMMF in our series is associated with a lower rate of post salvage laryngectomy fistulas in patients treated primarily by organ preservation protocol for laryngeal/hypopharyngeal cancer. In turn, it promotes local healing by decreasing the mean duration of fistula closure and the mean hospital stay.
咽皮肤瘘是全喉切除术后最常见的并发症。其发生率在初次全喉切除术后患者中为9%-25%,在放疗后或化疗+放疗后的挽救性喉切除术后患者中为14%-57%。胸大肌肌筋膜瓣(PMMF)被认为是降低该并发症发生率的有效工具。
对一组接受挽救性喉切除术的患者进行回顾性分析,这些患者是否联合使用PMMF进行咽闭合加强术。
纳入20例患者,其中男性18例(90%),女性2例(10%),10例使用了PMMF。平均年龄为66.65岁。17例(85%)患有喉肿瘤,3例(15%)患有下咽肿瘤。非PMMF组8例(80%)患者术后发生瘘管,而PMMF组仅2例(20%)患者在术后发生瘘管(P=0.005)。使用PMMF瓣的病例中,瘘管闭合的平均时间明显更短(16±11天 vs. 76.8±67天,P=0.001),住院时间也是如此(19.6±18天 vs. 83.9±77天,P=0.001)。
在我们的系列研究中,对于主要采用喉/下咽癌器官保留方案治疗的患者,使用PMMF与挽救性喉切除术后较低的瘘管发生率相关。反过来,它通过缩短瘘管闭合的平均持续时间和平均住院时间促进局部愈合。