Mean residence time for drugs subject to reversible metabolism.
作者信息
Aarons L
出版信息
J Pharm Pharmacol. 1987 Jul;39(7):565-7. doi: 10.1111/j.2042-7158.1987.tb03181.x.
Abstract
Conventional methods based on moment analysis lead to biased estimates of the mean residence time for drugs subject to reversible metabolism. A stochastic approach is described which enables unbiased estimation of the mean residence time.
摘要
Zotero 插件