Département de médecine générale, Faculté de médecine, Université de Rennes 1, France.
Normandie Univ, Unicaen, Inserm U1086, Cancers et préventions, et CHU Caen, Caen, France.
Dig Liver Dis. 2017 Nov;49(11):1267-1272. doi: 10.1016/j.dld.2017.08.018. Epub 2017 Aug 10.
The reasons for participation in fecal immunological testing (FIT) of subjects who were previously non-respondents to guaiac fecal occult blood testing (g-FOBT) have not been assessed.
We aimed to determine the reasons for current compliance with FIT among non-responders to g-FOBT, termed "converts‿, in a French district. A questionnaire was returned by 170 converts aged from 55 to 75 years (response rate 75.2% after exclusions).
The major barriers to participation in screening with g-FOBT were test-related: the test was perceived as complicated (24%) and it required three consecutive stools (28%). Among the test-related major determinants of FIT compliance was the perception that the test was less complicated than previous test (30%) and that a unique stool sample was required (29%). Among the non-test related major determinants of FIT compliance were the perception that the general practitioner was more convincing (31%) and the feeling to be more concerned because of age (21%). The reasons for compliance among converts did not differ according to age, sex, and rural or urban residence.
Our study demonstrated that the simplicity of FIT and the endorsement of practitioners were both major motivations for FIT compliance among non-respondents in at least two previous consecutive campaigns.
既往对愈创木脂粪便潜血试验（g-FOBT）无反应的受试者参与粪便免疫化学检测（FIT）的原因尚未得到评估。
我们旨在确定法国某地区既往对 g-FOBT 无反应者（称为“转化者”）目前对 FIT 依从的原因。对年龄在 55 至 75 岁之间的 170 名转化者进行了问卷调查（排除后应答率为 75.2%）。
参与 g-FOBT 筛查的主要障碍与检测相关：检测被认为复杂（24%），需要连续三次粪便样本（28%）。FIT 依从性的主要检测相关决定因素包括认为检测比之前的检测简单（30%）和只需要一份粪便样本（29%）。FIT 依从性的主要非检测相关决定因素包括认为全科医生更有说服力（31%）和因年龄增长而更关注（21%）。转化者的依从原因不因年龄、性别以及城乡居住而有所不同。
我们的研究表明，FIT 的简便性和医生的认可均是既往至少连续两次筛查活动中无反应者依从 FIT 的主要动机。
