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本文引用的文献

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Leech therapy in flap salvage: Systematic review and practical recommendations.水蛭疗法在皮瓣挽救中的应用：系统评价与实用建议。
Ann Chir Plast Esthet. 2017 Apr;62(2):e1-e13. doi: 10.1016/j.anplas.2016.06.004. Epub 2016 Jul 15.
2
Cutaneous complications of improper leech application.水蛭不当应用引起的皮肤并发症。
Ann Agric Environ Med. 2012;19(4):790-2.
3
Standardized protocol for artery-only fingertip replantation.仅动脉吻合的指尖再植标准化方案。
J Hand Surg Am. 2010 Sep;35(9):1491-6. doi: 10.1016/j.jhsa.2010.06.004.
4
Development of a mechanical device to replace medicinal leech (Hirudo medicinalis) for treatment of venous congestion.
J Rehabil Res Dev. 2002 Jul-Aug;39(4):497-504.
5
Sustained bleeding after a leech bite in the apparent absence of hirudin.在明显缺乏水蛭素的情况下，水蛭叮咬后持续出血。
Thromb Haemost. 1989 Jun 30;61(3):366-9.
6
Refined structure of the hirudin-thrombin complex.水蛭素-凝血酶复合物的精细结构
J Mol Biol. 1991 Sep 20;221(2):583-601. doi: 10.1016/0022-2836(91)80074-5.

小儿手部手术单次应用水蛭后出血时间延长

Prolonged Bleeding after a Single Leech Application in Pediatric Hand Surgery.

作者信息

Kotick James D, Taghinia Amir

机构信息

Department of Plastic, Reconstructive, and Hand Surgery, Lahey Hospital and Medical Clinic, Tufts Medical School, Burlington, Massachusetts, United States.

Department of Plastic and Hand Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States.

出版信息

J Hand Microsurg. 2017 Aug;9(2):98-100. doi: 10.1055/s-0037-1604348. Epub 2017 Jul 21.

DOI:10.1055/s-0037-1604348
PMID:28867911
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5578820/
Abstract

Use of the medicinal leech in microsurgery is common place for venous decongestion and can be associated with the need for transfusion over time and multiple applications. Here the authors present a case of profound, ongoing, life-threatening bleeding after a single leech application in pediatric microscopic surgery. There are no reports of such profound bleeding in the literature, and this case serves as a warning of the need for close surveillance in this subset of patients.

摘要

医用水蛭在显微外科手术中常用于静脉充血，随着时间推移和多次应用可能需要输血。本文作者报告了一例小儿显微外科手术单次应用水蛭后出现严重、持续、危及生命的出血病例。文献中尚无此类严重出血的报道，该病例警示了对此类患者进行密切监测的必要性。