Bapat R D, Acharya B S, Juvekar S, Dahanukar S A
Department of General Surgery, Therapeutics & Ayurveda Research Centre, Seth G.S. Medical College, Mumbai.
Indian J Med Res. 1998 Jun;107:281-4.
Several methods of limb bandaging have been described to reduce the oedema and enhance ulcer healing in complicated varicose veins, with varying success rates. Leech therapy has never before been tried for the same. We evaluated the effectiveness of medicinal leech therapy in producing venous decongestion, reversal of oedema, hyperpigmentation and healing of varicose ulcer(s). Whether the leech selectively sucks venous blood was also investigated. Hirudo medicinalis (medicinal leech) was applied to the area surrounding the varicose ulcer(s) in 20 patients with varicose veins with complications and the patients monitored for ulcer healing, and decrease in hyperpigmentation, oedema and limb girth. The partial pressure of O2 (pO2) of 7 patients' arterial and venous blood was compared to that sucked by the leech. After leech therapy all the ulcers showed healing, while 95 per cent of patients showed a decrease in oedema and limb girth. Seventy five per cent patients demonstrated a decrease in hyperpigmentation. The mean pO2 of blood sucked by the leech was 40.05 +/- 7.24 mmHg, which was similar to the mean pO2 of the patients' venous blood (34.33 +/- 8.4 mmHg). Thus it appears from this study that the medicinal leech sucks venous blood and aids ulcer healing, and can probably therefore be used as an effective adjunct in the management of complicated varicose veins. This however requires further evaluation by controlled trials.
为减轻水肿并促进复杂静脉曲张患者的溃疡愈合,人们已描述了多种肢体包扎方法,但其成功率各不相同。水蛭疗法此前从未用于此。我们评估了药用蚂蟥疗法在促进静脉血液回流、消除水肿、减轻色素沉着以及治愈静脉曲张性溃疡方面的有效性。我们还研究了水蛭是否有选择性地吸食静脉血。将医用水蛭应用于20例患有并发症的静脉曲张患者的静脉曲张性溃疡周围区域,并对患者的溃疡愈合情况以及色素沉着、水肿和肢体周长的减少情况进行监测。比较了7例患者动脉血和静脉血的氧分压(pO2)与水蛭吸食的血液的氧分压。水蛭疗法后,所有溃疡均愈合,95%的患者水肿和肢体周长减小。75%的患者色素沉着减轻。水蛭吸食的血液的平均pO2为40.05±7.24 mmHg,与患者静脉血的平均pO2(34.33±8.4 mmHg)相似。因此,从这项研究来看,医用水蛭吸食静脉血并有助于溃疡愈合,因此可能可作为治疗复杂静脉曲张的一种有效辅助手段。然而,这需要通过对照试验进行进一步评估。