局部性落叶型天疱疮病例中病灶内注射类固醇的应用

Ghoneim Sara, Zaiac Martin

Saba University School of Medicine, The Bottom, Netherlands Antilles.

Department of Dermatology, Herbert Wertheim College of Medicine, Florida International University, Greater Miami Skin and Laser Center, Miami, Florida, USA.

Case Rep Dermatol. 2017 Jul 13;9(2):91-97. doi: 10.1159/000477959. eCollection 2017 May-Aug.

A 37-year-old South-Asian male presented to our clinic with a crusty, verrucous-like, scaly plaque of the left ala of the nose. After ruling out infectious and other epidermal bullous diseases, we finalized a diagnosis of localized pemphigus foliaceus, an exceptionally rare disorder with only 15 cases reported in the literature to date. The hyperkeratotic lesions responded favorably to a 3-week regimen of triamcinolone ointment and a onetime intralesional triamcinolone 2.5 mg/mL injection.

一名37岁的南亚男性前来我们诊所就诊，其左侧鼻翼有一块结痂、疣状、鳞屑性斑块。在排除感染性疾病和其他表皮大疱性疾病后，我们最终诊断为局限性落叶型天疱疮，这是一种极为罕见的疾病，迄今为止文献中仅报道过15例。经3周的曲安奈德软膏治疗方案以及一次2.5mg/mL的曲安奈德皮损内注射后，角化过度性皮损反应良好。